000			03069nam a22005057a 4500
008			240723s20242024 xxu||||| |||| 00| 0 eng d
022			_a0165-5876
024			_aS0165-5876(24)00044-2 [pii]
040			_aOvid MEDLINE(R)
099			_a38531270
245			_aRisk of post-tonsillectomy hemorrhage among COVID-19 positive pediatric patients.
251			_aInternational Journal of Pediatric Otorhinolaryngology. 179:111890, 2024 Apr.
252			_aInt J Pediatr Otorhinolaryngol. 179:111890, 2024 Apr.
253			_aInternational journal of pediatric otorhinolaryngology
260			_c2024
260			_p2024 Apr
260			_fFY2024
265			_sppublish
265			_tMEDLINE
520			_aCONCLUSION: The results of this investigation suggest that the presence of COVID-19 in the perioperative period may pose an increased risk for acute or delayed post tonsillectomy hemorrhage. This study employed a large, diverse population and is the first to address this clinical question. Copyright © 2024. Published by Elsevier B.V.
520			_aMETHODS: The TriNetX database was queried for pediatric patients who underwent tonsillectomy and evaluated for outcomes of primary and secondary post-tonsillectomy hemorrhage.
520			_aOBJECTIVE: COVID-19 infection has been demonstrated to increase risk for post-operative bleeding. This study investigated the impact of COVID-19 infection on post-tonsillectomy hemorrhage in pediatric patients, a potentially devastating complication.
520			_aRESULTS: Among subjects 18 years and younger, 1226 were COVID-19 positive and 38,241 were COVID-19 negative in the perioperative period. There was statistically significant increased risk of bleeding with perioperative COVID-19 infection at postoperative days 1, 5, and 10. Additionally, when assessing the role of COVID-19 infection before or after surgery, the risk of bleeding remained statistically significant at all three time points, however these results did not suggest that infection before surgery confers more/less risk compared to infection after.
520			_aSTUDY DESIGN: Retrospective cohort study.
546			_aEnglish
650			_a*COVID-19
650			_a*Tonsillectomy
650			_aChild
650			_aCOVID-19/co [Complications]
650			_aHumans
650			_aPostoperative Hemorrhage/ep [Epidemiology]
650			_aPostoperative Hemorrhage/et [Etiology]
650			_aPostoperative Period
650			_aRetrospective Studies
650			_aTonsillectomy/ae [Adverse Effects]
650			_aTonsillectomy/mt [Methods]
650			_zAutomated
656			_aMedStar Georgetown University Hospital/MedStar Washington Hospital Center
656			_aOtolaryngology Residency
657			_aJournal Article
700			_aLeonard, James _bMGUH _cOtolaryngology Residency _dMD
790			_aMartin AM, Elliott ZT, Leonard JA, Maxwell JH, Scriven K, Harley E
856			_uhttps://dx.doi.org/10.1016/j.ijporl.2024.111890 _zhttps://dx.doi.org/10.1016/j.ijporl.2024.111890
942			_cART _dArticle
999			_c14304 _d14304