000			03415nam a22004937a 4500
008			240807s20242024 xxu||||| |||| 00| 0 eng d
022			_a2000-9666
024			_ajchim-14-02-023 [pii]
024			_aPMC11221445 [pmc]
040			_aOvid MEDLINE(R)
099			_a38966513
245			_aOutcome Comparison in Hospitalized COVID-19 Patients With and Without AKI.
251			_aJournal of Community Hospital Internal Medicine Perspectives. 14(2):23-29, 2024.
252			_aJ Community Hosp Intern Med Perspect. 14(2):23-29, 2024.
253			_aJournal of community hospital internal medicine perspectives
260			_c2024
260			_fFY2025
260			_p2024
265			_sepublish
265			_tPubMed-not-MEDLINE
266			_d2024-08-07
266			_z2024/07/05 04:10
520			_aAim: Patients hospitalized with COVID-19 have a higher incidence of Acute Kidney Injury (AKI) compared with non-COVID patients. Previous observational studies showed AKI in hospitalized patients with COVID-19 was associated with significant increased mortality rate. We conducted a retrospective cohort study in a large mid-Atlantic health system to investigate whether COVID-19 associated AKI during hospitalization would lead to worse outcomes in a predominant Black patient population, compared to COVID-19 without AKI.
520			_aConclusions: AKI in hospitalized patients with COVID-19 was associated with higher mortality rate, need for intubation and ICU admission compared to COVID-19 patients without AKI group. Copyright © 2024 Greater Baltimore Medical Center.
520			_aMethods: We reviewed health records of patients (aged>=18 years) admitted with symptomatic COVID-19 between March 5, 2020, and Jun 3, 2020, in 9 acute care facilities within the MedStar Health system. Patients were followed up until 3 months after discharge. Primary outcome was inpatient mortality. Secondary outcomes were need for ICU level of care, need for intubation, length of ICU stay, length of hospital stay, need for renal replacement therapy, recovery of renal function.
520			_aResults: Among 1107 patients admitted with symptomatic COVID-19, the AKI incidence rate was 35 %. African American patients made up 63 % of the total patient population and 74 % of the total AKI population. Inpatient mortality in the AKI group and the non-AKI group was 163 (41.9 %) and 71 (9.9 %), respectively. COVID-19 patients with AKI had significant higher risk of in-patient mortality (OR, 4.71 [95 % CI, 3.38-6.62], P < 0.001), ICU admission (OR, 4.27 [95 % CI, 3.21-5.72], P < 0.001) and need of intubation (OR, 6.18 [95 % CI, 4.45-8.68], P < 0.001).
546			_aEnglish
650			_zAutomated
651			_aMedStar Health Research Institute
651			_aMedStar Union Memorial Hospital
656			_aInternal Medicine Residency
656			_aMedicine
656			_aNephrolgy
657			_aJournal Article
700			_aChou, JiLing _bMHRI
700			_aDhillon, Monika _bMUMH
700			_aHalik, Abraham
700			_aNajafi, Wajehe _bMUMH
700			_aWeisman, David S _bMUMH
700			_aZhang, Yani _bMUMH _cInternal Medicine Residency _dMMed
790			_aShrestha S, Zhang Y, Najafi W, Halik A, Chou J, Michael Siu MK, Dhillon M, Weisman DS
856			_uhttps://dx.doi.org/10.55729/2000-9666.1320 _zhttps://dx.doi.org/10.55729/2000-9666.1320
942			_cART _dArticle
999			_c14464 _d14464