000 02294nam a22003977a 4500
008 240807s20242024 xxu||||| |||| 00| 0 eng d
022 _a2152-7806
024 _a10.25259/SNI_135_2024 [pii]
024 _aPMC11152506 [pmc]
040 _aOvid MEDLINE(R)
099 _a38840603
245 _aRelationship between 25-hydroxy Vitamin D level and surgical site infection in spine surgery.
251 _aSurgical neurology international. 15:173, 2024.
252 _aSurg Neurol Int. 15:173, 2024.
253 _aSurgical neurology international
260 _c2024
260 _fFY2024
260 _p2024
265 _sepublish
265 _tPubMed-not-MEDLINE
266 _d2024-08-07
266 _z2024/06/06 03:44
520 _aBackground: 25-hydroxy Vitamin D (25[OH]D) level has been shown to have antimicrobial and wound healing effects in animal models. Low preoperative 25(OH)D has been shown to correlate with surgical site infection (SSI) in thoracolumbar spine surgery.
520 _aConclusion: SSI rates following thoracolumbar spine surgery were not affected by preoperative 25(OH)D levels. Copyright: © 2024 Surgical Neurology International.
520 _aMethods: This study involved 545 patients undergoing thoracolumbar spine surgery from 2012 to 2019 at an academic medical center. We evaluated the serum 25(OH)D level (i.e., adequate level = level 30-60 ng/dL), along with SSI, body mass index, and smoking status. Statistical analysis was done using bivariate analysis with Fisher's exact, Wilcoxon rank-sum test and multivarible logisitic regression analyses.
520 _aResults: We included 545 patients in the study, and there were no statistical differences in the average preoperative 25(OH)D between SSI and non-SSI groups. The average 25(OH)D in the non-SSI group was 31.6 ng/dL +/- 13.6, and the SSI group was 35.7 ng/dL +/- 20.2 (P = 0.63).
546 _aEnglish
650 _zAutomated
651 _aMedStar Washington Hospital Center
656 _aOrthopedics
657 _aJournal Article
700 _aMesfin, Addisu
_bMWHC
790 _aLiu S, Sulovari A, Joo P, Thirukumaran C, Benn L, Mesfin A
856 _uhttps://dx.doi.org/10.25259/SNI_135_2024
_zhttps://dx.doi.org/10.25259/SNI_135_2024
942 _cART
_dArticle
999 _c14487
_d14487