000 03340nam a22003617a 4500
008 240807s20242024 xxu||||| |||| 00| 0 eng d
022 _a2168-8184
024 _aPMC11144579 [pmc]
040 _aOvid MEDLINE(R)
099 _a38832202
245 _aE-cigarette Use and Severe Coronavirus Disease 2019 (COVID-19) Outcomes: A Meta-Analysis. [Review]
251 _aCureus. 16(5):e59591, 2024 May.
252 _aCureus. 16(5):e59591, 2024 May.
253 _aCureus
260 _c2024
260 _fFY2024
260 _p2024 May
265 _sepublish
265 _tPubMed-not-MEDLINE
266 _d2024-08-07
266 _z2024/06/04 03:44
520 _aE-cigarettes have been known to cause varied poor health outcomes prior to coronavirus disease 2019 (COVID-19), but after the impact of COVID-19, evidence came out that was, in some instances, not as expected regarding the severity of COVID-19 among e-cigarette users (vapers). A meta-analysis was performed on the available evidence to comprehensively find the effect of COVID-19 on existing or past e-cigarette users (vapers). The Meta-analysis of Observational Studies in Epidemiology (MOOSE) guidelines were used to perform this meta-analysis. PubMed was searched for observational studies that described outcomes after COVID-19 positivity from December 1, 2019, to December 2023. Medical Subject Headings (MeSH) keywords were used for searching the relevant studies highlighting the relationship between COVID-19 and e-cigarette users. Calculations for pooled prevalence, 95% confidence interval (95% CI), weights for current e-cigarette users and vapers, and outcomes (events) were made. To analyze the data, Review Manager V.5.4 was used. The I2 statistic was used to assess statistical heterogeneity. The I2 statistic of >50% was considered significant heterogeneity. The "leave-one-out" method was used for sensitivity analysis. Out of 3231 studies, four studies reported data on vaping and non-vaping status and composite outcomes, resulting in a sample size of 653 COVID-19-positive cases. The pooled prevalence of being COVID-19 positive, having symptoms, or visiting an emergency room was 7.78% (653/8392). COVID-19 patients with current vaping status had decreased odds of poor outcomes compared to non-smokers, with a pooled odds ratio (OR) of 0.09 (95% CI 0.00-2.42; p>0.05) with heterogeneity between studies (I2=99%, p=0.15). Because of difficulties related to data collection and other factors, this meta-analysis was unable to conclusively establish the correlation between e-cigarette usage and severe COVID-19 outcomes such as hospitalization, admission to the intensive care unit, and fatality. Additional research using more detailed data is necessary to fully understand this correlation. Copyright © 2024, Valadez-Cuen et al.
546 _aEnglish
650 _zAutomated
651 _aMedStar Good Samaritan Hospital
656 _aHospital Medicine
657 _aJournal Article
657 _aReview
700 _aShah, Viray
_bMGSH
790 _aValadez-Cuen K, Bhatt T, Mendez IE, Solanki D, Abdi N, Shelar V, Akplor JJ, Reddy Bhumanapalli SA, Vinyak S, Patel D, Tirupathi R, Shah V, Patel UK, Rana RK
856 _uhttps://dx.doi.org/10.7759/cureus.59591
_zhttps://dx.doi.org/10.7759/cureus.59591
942 _cART
_dArticle
999 _c14488
_d14488