000			03665nam a22004457a 4500
008			240807s20242024 xxu||||| |||| 00| 0 eng d
022			_a2049-9361
024			_a10.1177_20499361241252351 [pii]
024			_aPMC11095193 [pmc]
040			_aOvid MEDLINE(R)
099			_a38751758
245			_aAge-related factors associated with intention to initiate pre-exposure prophylaxis among cisgender women in Washington D.C.
251			_aTherapeutic Advances in Infectious Disease. 11:20499361241252351, 2024 Jan-Dec.
252			_aTher. adv. infect. dis.. 11:20499361241252351, 2024 Jan-Dec.
253			_aTherapeutic advances in infectious disease
260			_c2024
260			_fFY2024
260			_p2024 Jan-Dec
265			_sepublish
265			_tPubMed-not-MEDLINE
266			_d2024-08-07
266			_z2024/05/16 03:41
520			_aBackground: Pre-exposure prophylaxis (PrEP) utilization among cisgender women (subsequently 'women') is low across age groups, relative to their risk of HIV acquisition. We hypothesize that age-related differences in psychosocial factors also influence women's intention to initiate oral PrEP in Washington, D.C.
520			_aConclusion: Overall, there were more similarities than differences in factors influencing intention to initiate PrEP across age groups. Observed differences offer an opportunity to tailor PrEP delivery and HIV prevention interventions to increase awareness and uptake for cisgender women. Copyright © The Author(s), 2024.
520			_aMethods: A secondary analysis of a cross-sectional survey data was performed to evaluate factors influencing intention to initiate oral PrEP among women seen at a family planning and a sexual health clinic. A bivariate analysis was performed to identify differences by age group in demographic characteristics, indications for PrEP, and attitudes toward PrEP; we then performed additional bivariate analysis to assess these variables in relation to PrEP intention.
520			_aResults: Across age groups, perceived risk of HIV acquisition was not significantly different and was not associated with intention to initiate PrEP. Awareness of and attitude toward PrEP, injunctive norms, descriptive norms, and self-efficacy were not different across age, however there were significant age-associated differences in relation to PrEP intention. Specifically, among 18-24-year-olds, intention to start PrEP was associated with support from provider (p = 0.03), main sexual partner (p < 0.01), and peers (p < 0.01). For women 25-34 years old, having multiple sexual partners (p = 0.03) and support from casual sexual partners (p = 0.03) was also important. Among women 35-44 years old, prior awareness of PrEP (p = 0.02) and their children's support of PrEP uptake (p < 0.01) were associated with intention to initiate PrEP. Among 45-55 year-old women intention to initiate PrEP was positively associated with engaging in casual sex (p = 0.03) and negatively associated with stigma (p < 0.01).
546			_aEnglish
650			_zAutomated
651			_aMedStar Health Research Institute
651			_aMedStar Washington Hospital Center
656			_aObstetrics and Gynecology/Family Planning
657			_aJournal Article
700			_aLotke, Pamela S _bMWHC
700			_aMoriarty, Patricia _bMHRI
700			_aScott, Rachel K _bMHRI
700			_aYe, Peggy Peng _bMWHC
790			_aZack JL, Hull SJ, Coleman ME, Ye PP, Lotke PS, Visconti A, Beverley J, Brant A, Moriarty P, Scott RK
856			_uhttps://dx.doi.org/10.1177/20499361241252351 _zhttps://dx.doi.org/10.1177/20499361241252351
942			_cART _dArticle
999			_c14502 _d14502