000 02950nam a22004217a 4500
008 241030s20242024 xxu||||| |||| 00| 0 eng d
022 _a1523-3782
024 _a10.1007/s11886-024-02113-7 [pii]
040 _aOvid MEDLINE(R)
099 _a39115799
245 _aChagas Disease: Epidemiology, Diagnosis, and Treatment. [Review]
251 _aCurrent Cardiology Reports. 2024 Aug 08
252 _aCurr Cardiol Rep. 2024 Aug 08
253 _aCurrent cardiology reports
260 _c2024
260 _fFY2025
260 _p2024 Aug 08
265 _saheadofprint
265 _tPublisher
266 _d2024-10-30
266 _z2024/08/08 11:16
520 _aFUTURE RESEARCH: Use of antiparasitics during chronic chagas disease should be further explored. Additionally, future research identifying other markers of infection would be valuable to defining cure from infection. Copyright © 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
520 _aPURPOSE OF REVIEW: This review seeks to describe the updates in the literature - particularly with regards to the epidemiology and diagnosis of Chagas disease. Additionally, this paper describes updates to the antiparasitic treatment for Chagas disease.
520 _aRECENT FINDINGS: With regards to changing epidemiology, autochthonous cases are being found within the USA in addition to Latin America. Additionally, there appears to be more intermixing of discrete typing units-meaning, they are not confined to specific geographic regions. Screening for Chagas disease is recommended in persons who lived in areas with endemic Chagas, persons wtih family member diagnosed with Chagas Disease, persons who have lived in homes of natural material in Latin America, and persons with history of kissing bug bites. Treatment for the parasitic infection remains limited to benznidazole and nifurtimox, and the role of these treatments in Chagas cardiomyopathy has not yet been definitively defined. Finally, indications for and management of heart transplant in the setting of Chagas disease are discussed.
546 _aEnglish
650 _aIN PROCESS -- NOT YET INDEXED
656 _aInternal Medicine Residency
656 _aMedStar Georgetown University Hospital/MedStar Washington Hospital Center
657 _aJournal Article
657 _aReview
700 _aRayes, Danny
_bMGUH
_cInternal Medicine Residency
_dMD
700 _aSwett, Michael
_bMGUH
_cInternal Medicine Residency
_dMD
790 _aSwett MC, Rayes DL, Campos SV, Kumar RN
856 _uhttps://dx.doi.org/10.1007/s11886-024-02113-7
_zhttps://dx.doi.org/10.1007/s11886-024-02113-7
858 _yRayes, Danny L
_uhttp://orcid.org/0000-0002-5656-5305
_zhttp://orcid.org/0000-0002-5656-5305
858 _ySwett, Michael C
_uhttp://orcid.org/0009-0000-2024-5521
_zhttp://orcid.org/0009-0000-2024-5521
942 _cART
_dArticle
999 _c14699
_d14699