000 03554nam a22003977a 4500
008 241030s20242024 xxu||||| |||| 00| 0 eng d
022 _a1932-2259
024 _a10.1007/s11764-024-01638-8 [pii]
040 _aOvid MEDLINE(R)
099 _a39083112
245 _aFunctional limitations among adult cancer survivors in the United States.
251 _aJournal of Cancer Survivorship. 2024 Jul 31
252 _aJ. cancer surviv.. 2024 Jul 31
253 _aJournal of cancer survivorship : research and practice
260 _c2024
260 _fFY2025
260 _p2024 Jul 31
265 _saheadofprint
265 _tPublisher
266 _d2024-10-30
266 _z2024/07/31 11:06
520 _aCONCLUSIONS: Cancer was associated with limitations across age groups, with the highest age-stratified ORs observed among younger adults and for mobility and lower-extremity limitations. Stronger efforts to assess limitations as part of routine care and implement targeted interventions to address limitations are needed.
520 _aIMPLICATIONS FOR CANCER SURVIVORS: Functional limitations have been linked with poorer aging trajectories and lower quality of life in cancer and non-cancer populations. Routine screening to identify and discuss functional limitations with cancer patients may help reduce the burden of such limitations on survivors. Copyright © 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
520 _aMETHODS: Participants were 151,509 adults in the 2014-2018 NHIS. Functional limitations included self-reported difficulty conducting nine activities. Data were analyzed using age-stratified multivariate logistic regression (no limitation vs. limited in any way; minor limitation vs. major limitation) and are reported as covariate-adjusted odds ratios (ORs) and 95% confidence intervals (95% CIs). To gather insight on the influence of cancer, compared to aging without a history of cancer, on functional limitations, we also conducted exploratory regression analyses comparing all cancer by age groups to 18-44 year-olds without a cancer history.
520 _aPURPOSE: Using data from the National Health Interview Survey (NHIS), this study examined the odds of functional limitations across nine domains by cancer status (with vs. without cancer history) and age group (18-44, 45-64, 65 + years).
520 _aRESULTS: Cancer survivors (n = 12,518) were more likely to report a limitation than adults without cancer (n = 138,991). Age-stratified ORs for 1 + limitation were 2.75 (95% CI 1.98, 3.81) among 18-44 year-olds, 2.42 (95% CI 2.00, 2.93) among 45-64 year-olds, and 1.59 (95% CI 1.39, 1.82) among 65 + year-olds. Cancer survivors were more likely to report major limitations across multiple domains, with age-stratified ORs ranging from 1.18 (65 + year-olds, stooping limitation) to 2.28 (18-44 year-old, sitting limitation). ORs from exploratory analyses were lowest among 45-64 year-old adults without a cancer history (2.69-4.42) and highest among older adult cancer survivors (3.42-14.73).
546 _aEnglish
650 _zAutomated
650 _aIN PROCESS -- NOT YET INDEXED
651 _aMedStar Health Research Institute
657 _aJournal Article
700 _aArem, Hannah
_bMHRI
790 _aEhlers DK, Weaver N, Ma J, Mama SK, Page LL, Rowland J, Arem H
856 _uhttps://dx.doi.org/10.1007/s11764-024-01638-8
_zhttps://dx.doi.org/10.1007/s11764-024-01638-8
942 _cART
_dArticle
999 _c14705
_d14705