000			03039nam a22003377a 4500
008			170428s20172017 xxu||||| |||| 00| 0 eng d
022			_a2213-0071
040			_aOvid MEDLINE(R)
099			_a27920974
245			_aA case report of malignant obesity hypoventilation syndrome: A weighty problem in our ICUs.
251			_aRespiratory Medicine Case Reports. 20:38-41, 2017
252			_aRespir Med Case Rep. 20:38-41, 2017
253			_aRespiratory medicine case reports
260			_c2017
260			_fFY2017
266			_d2017-05-06
520			_aCASE PRESENTATION: 35 year old African American gentleman with a body mass index (BMI) of 115 kg/m<sup>2</sup> presented to the hospital with respiratory distress. On admission he was noted to have multi-organ dysfunction including respiratory failure, renal failure, cardiac and liver abnormalities. His hospital course was remarkable for recurrent cardiac arrest following extubation, complicated tracheostomy, and progressive organ failure despite medical therapy. After a 30 day hospitalization, patient and family decided on terminal extubation owing to worsening medical condition and lack of therapeutic and disposition options.
520			_aCONCLUSION: Physicians should be aware of MOHS as a common condition with high morbidity and mortality. Optimal management remains to be determined.
520			_aDISCUSSION: The super obese present a number of challenges when admitted to the ICU. Patients with respiratory distress are frequently misdiagnosed and treated for asthma and COPD when obesity hypoventilation syndrome (OHS) is more consistent with the clinical picture. OHS in the superobese is often accompanied by multi-system organ dysfunction, a condition with high morbidity and mortality, with limited treatment options. Standard imaging techniques and procedures are made difficult or impossible by body habitus and often require expert intervention. Surgical options have been used in the treatment of the super obese and resulted in rapid weight loss, improvement in respiratory function, as well as improved metabolism and decreased inflammation. The role of surgery in MOHS remains to be elucidated.
520			_aINTRODUCTION: The obesity epidemic is reflected by increasing numbers of morbidly obese patients being admitted to intensive care units (ICUs). These are complicated patients whose care involves many diagnostic and treatment challenges. We are presenting a fatal case of super obesity, hypoventilation, and multi-organ failure known as malignant obesity hypoventilation syndrome (MOHS).
546			_aEnglish
650			_aPubMed-not-MEDLINE -- Not indexed
651			_aMedStar Washington Hospital Center
656			_aMedicine/Pulmonary-Critical Care
657			_aJournal Article
700			_aCuneo, Brian M
700			_aTatusov, Michael
790			_aCuneo BM, Joseph JJ, Tatusov M
856			_uhttps://dx.doi.org/10.1016/j.rmcr.2016.11.005 _zhttps://dx.doi.org/10.1016/j.rmcr.2016.11.005
942			_cART _dArticle
999			_c2189 _d2189