000			03645nam a22006257a 4500
008			170411s20162016 xxu||||| |||| 00| 0 eng d
022			_a0029-7844
040			_aOvid MEDLINE(R)
099			_a27400012
245			_aDuration of Oxytocin and Rupture of the Membranes Before Diagnosing a Failed Induction of Labor.
251			_aObstetrics & Gynecology. 128(2):373-80, 2016 Aug
252			_aObstet Gynecol. 128(2):373-80, 2016 Aug
253			_aObstetrics and gynecology
260			_c2016
260			_fFY2017
266			_d2017-05-24
501			_aAvailable online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006
520			_aCONCLUSION: Based on when neonatal morbidity increased, in an otherwise uncomplicated induction of labor with rupture of membranes, a latent phase after initiation of oxytocin of at least 12 hours for nulliparous women and 15 hours in multiparous women is a reasonable criterion for diagnosing a failed induction.
520			_aMETHODS: This is a retrospective cohort study using data from the Consortium of Safe Labor study, including 9,763 nulliparous and 8,379 multiparous women with singleton, term pregnancies undergoing induction at 2 cm dilation or less with rupture of membranes before 6 cm dilation after which the latent phase ended. Outcomes were evaluated according to duration of oxytocin and rupture of membranes.
520			_aOBJECTIVE: To compare maternal and neonatal outcomes based on length of the latent phase during induction with rupture of membranes before 6 cm dilation.
520			_aRESULTS: At time points from 6 to 18 hours of oxytocin and rupture of membranes, the rates of nulliparous women remaining in the latent phase declined (35.9-1.4%) and the rates of vaginal delivery for those remaining in the latent phase at these time periods decreased (54.1-29.9%) Nulliparous women remaining in the latent phase for 12 hours compared with women who had exited the latent phase had significantly increased rates of chorioamnionitis (12.1% compared with 4.1%) and endometritis (3.6% compared with 1.3%) and increased rates of neonatal intensive care unit admission (8.7% compared with 6.3%). Similar patterns were present for multiparous women at 15 hours.
546			_aEnglish
650			_a*Extraembryonic Membranes
650			_a*Labor, Induced
650			_a*Labor, Obstetric
650			_a*Oxytocics/ad [Administration & Dosage]
650			_a*Oxytocin/ad [Administration & Dosage]
650			_aAdult
650			_aChorioamnionitis/ep [Epidemiology]
650			_aEndometritis/ep [Epidemiology]
650			_aFemale
650			_aHumans
650			_aInfant, Newborn
650			_aIntensive Care, Neonatal/sn [Statistics & Numerical Data]
650			_aLabor, Obstetric/de [Drug Effects]
650			_aParity
650			_aPregnancy
650			_aRetrospective Studies
650			_aTime Factors
650			_aTreatment Failure
650			_aYoung Adult
651			_aMedStar Health Research Institute
651			_aMedStar Washington Hospital Center
656			_aObstetrics and Gynecology/Maternal-Fetal Medicine
657			_aJournal Article
700			_aGrantz, Katherine L
700			_aHuang, Chun Chih
700			_aIqbal, Sara N
700			_aKawakita, Tetsuya
700			_aLandy, Helain J
700			_aReddy, Uma M
790			_aGrantz KL, Hoffman M, Huang CC, Iqbal SN, Kawakita T, Landy HJ, Reddy UM, Sciscione AC
856			_uhttps://dx.doi.org/10.1097/AOG.0000000000001527 _zhttps://dx.doi.org/10.1097/AOG.0000000000001527
942			_cART _dArticle
999			_c2424 _d2424