000			04317nam a22008057a 4500
008			190408s20182018 xxu||||| |||| 00| 0 eng d
022			_a1878-0938
024			_a10.1016/j.carrev.2017.10.002 [doi]
024			_aS1553-8389(17)30389-5 [pii]
040			_aOvid MEDLINE(R)
099			_a29153508
245			_aPatient characteristics in variable left ventricular recovery from Takotsubo syndrome.
251			_aCardiovascular Revascularization Medicine. 19(3 Pt A):247-250, 2018 04.
252			_aCardiovasc Revasc Med. 19(3 Pt A):247-250, 2018 04.
253			_aCardiovascular revascularization medicine : including molecular interventions
260			_c2018
260			_fFY2018
265			_sppublish
266			_d2017-12-05
501			_aAvailable in print through MWHC library: 2002 - present
520			_aBACKGROUND: Takotsubo syndrome (TTS) is a heart failure syndrome which is usually reversible. Factors associated with degree of recovery of left ventricular systolic function in TTS are poorly understood.
520			_aCONCLUSION: Takotsubo patients with partial myocardial recovery were older, presented with longer QT intervals, and were more likely to have comorbid hypothyroidism.
520			_aCopyright (c) 2017 Elsevier Inc. All rights reserved.
520			_aMATERIALS AND METHODS: We conducted a retrospective analysis of 90 TTS patients treated at our institution from 2006 to 2014. Patients were grouped based on recovery of left ventricular ejection fraction (LVEF) on follow-up transthoracic echocardiogram as left ventricular ejection fraction <50% (partial group) or preserved ejection fraction >=50% (full group). Patient baseline characteristics, comorbidities, biomarkers, electrocardiography, and echocardiogram were collected. We also compared adverse events that occurred during hospitalization.
520			_aRESULTS: In comparison to full recovery group patients (n=63), partial recovery patients (n=27) were older (76.9+/-13 vs. 70.6+/-13years; P=0.02) and had a higher prevalence of comorbid hypothyroidism (26% vs. 8%; P=0.02). A greater number of patients from the partial group were also taking levothyroxine replacement (22% vs. 3%; P=0.003). We found no significant between-group differences in type of triggering event or cardiac biomarker levels. QT interval was longer in the partial group (540.6+/-71msec vs. 460.7+/-35msec; P=0.01). Follow-up LVEF was 37.9+/-8% in the partial group and 58.0+/-4% in the full group (P<0.001). There were no statistically significant differences in length of stay or adverse events.
546			_aEnglish
650			_a*Stroke Volume
650			_a*Takotsubo Cardiomyopathy/pp [Physiopathology]
650			_a*Ventricular Function, Left
650			_aAction Potentials
650			_aAge Factors
650			_aAged
650			_aAged, 80 and over
650			_aComorbidity
650			_aEchocardiography
650			_aElectrocardiography
650			_aFemale
650			_aHeart Rate
650			_aHumans
650			_aHypothyroidism/ep [Epidemiology]
650			_aMale
650			_aMiddle Aged
650			_aPrevalence
650			_aRecovery of Function
650			_aRegistries
650			_aRetrospective Studies
650			_aTakotsubo Cardiomyopathy/di [Diagnosis]
650			_aTakotsubo Cardiomyopathy/ep [Epidemiology]
650			_aTakotsubo Cardiomyopathy/th [Therapy]
650			_aTime Factors
650			_aUnited States/ep [Epidemiology]
651			_aMedStar Heart & Vascular Institute
651			_aMedStar Washington Hospital Center
656			_aMedicine/Internal Medicine
657			_aJournal Article
700			_aAzzouqa, Alaa
700			_aBen-Dor, Itsik
700			_aKim, Jae I
700			_aKoiffman, Edward
700			_aLindsay, Joseph
700			_aPichard, Augusto D
700			_aSatler, Lowell F
700			_aTorguson, Rebecca
700			_aWaksman, Ron
700			_aWang, Zuyue
700			_aWeissman, Gaby
790			_aAzzouqa A, Ben-Dor I, Kim JI, Koiffman E, Lindsay J, Moran J, Pichard AD, Satler LF, Torguson R, Waksman R, Wang Z, Weissman G, Yerasi C
856			_uhttps://dx.doi.org/10.1016/j.carrev.2017.10.002 _zhttps://dx.doi.org/10.1016/j.carrev.2017.10.002
942			_cART _dArticle
999			_c2833 _d2833