000			03233nam a22003737a 4500
008			221018s20222022 xxu||||| |||| 00| 0 eng d
022			_a1918-2805
024			_a10.14740/gr1536 [doi]
024			_aPMC9451577 [pmc]
040			_aOvid MEDLINE(R)
099			_a36128186
245			_aEarly Colonoscopy in Hospitalized Patients With Acute Lower Gastrointestinal Bleeding: A Nationwide Analysis.
251			_aGastroenterology Research. 15(4):162-172, 2022 Aug.
252			_aGastroenterol. res.. 15(4):162-172, 2022 Aug.
253			_aGastroenterology research
260			_c2022
260			_fFY2023
260			_p2022 Aug
265			_sppublish
265			_tPubMed-not-MEDLINE
266			_d2022-10-20
520			_aBackground: Performing colonoscopy within 24 h of presentation to the hospital is the accepted standard of care for patients with an acute lower gastrointestinal bleed (LGIB). Previous studies have failed to demonstrate the benefit of early colonoscopy (EC) on mortality. In this study, we wanted to see if there was a change in inpatient deaths (primary outcome), length of stay (LOS), and hospitalization charges (TOTCHG) (secondary outcomes) with EC compared to previous studies.
520			_aConclusions: EC was not associated with decreased inpatient deaths. There was no difference in endoscopic interventions in both EC and DC groups. The difference in inpatient deaths observed between the two groups was not evident upon adjusting the results for confounders. EC was associated with a decreased LOS, and TOTCHG in patients with LGIB. Copyright 2022, Atodaria et al.
520			_aMethods: Adults diagnosed with LGIB were identified using the International Classification of Disease 10th Revision codes from the National Inpatient Sample database for 2016 to 2019. EC was defined as the procedure performed within 24 h of hospitalization. Delayed colonoscopy (DC) was defined as a procedure performed after 24 h of presentation. The patient population was divided into EC and DC groups, and the effects of several covariates on outcomes were measured using binary logistic and multivariate regression analysis. Inverse probability treatment weighting (IPTW) was performed to adjust for confounding covariates.
520			_aResults: There were 1,549,065 cases diagnosed with LGIB, of which 285,165 cases (18.4%) received a colonoscopy. A total of 107,045 (6.9%) patients received early colonoscopies. EC was associated with decreased inpatient deaths (0.9% in EC, and 1.4% in DC, P < 0.001). However, upon IPTW, this difference was not present. EC was associated with a decreased LOS (median 3 days vs. 5 days, P < 0.001) and TOTCHG (median _32,037 vs. _44,092, P < 0.001). Weekend admissions (WA) were associated with fewer EC (31.6% in WA, and 39.5% in non-WA, P < 0.001). WA did not affect inpatient deaths.
546			_aEnglish
650			_aIN PROCESS -- NOT YET INDEXED
656			_aMedStar St Mary's Hospital
657			_aJournal Article
700			_aDhruv, Samyak _bMSMH
790			_aAtodaria KP, Bhikadiya B, Bruno JM, Dhruv S, Ginnaram SR, Shah S
856			_uhttps://dx.doi.org/10.14740/gr1536 _zhttps://dx.doi.org/10.14740/gr1536
942			_cART _dArticle
999			_c310 _d310