000 01847nam a22003257a 4500
008 180220s20182018 xxu||||| |||| 00| 0 eng d
022 _a1757-790X
024 _a10.1136/bcr-2017-222373 [doi]
024 _abcr-2017-222373 [pii]
040 _aOvid MEDLINE(R)
099 _a29367365
245 _aCase of acute mixed liver injury due to hypothyroidism.
251 _aBMJ Case Reports. 2018, 2018 Jan 23
252 _aBMJ Case Rep. 2018, 2018 Jan 23
253 _aBMJ case reports
260 _c2018
260 _fFY2018
266 _d2018-02-20
520 _aCopyright (c) BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
520 _aThe effects of hypothyroidism on the liver are not well understood. A 77-year-old woman with Hashimoto's thyroiditis had stopped taking levothyroxine on her own for 6months. Her thyroid stimulating hormone (TSH) level was consistent with severe hypothyroidism. She resumed thyroid replacement therapy. The following month, her liver function tests were significantly elevated. Seven weeks after resumption of therapy, her TSH and liver tests had returned to normal. We attribute the mixed hepatocellular injury to hypothyroidism that resolved on correction of the hypothyroid state. This case reminds us that thyroid disease should be considered when evaluating acute liver injury.
546 _aEnglish
650 _aIN PROCESS -- NOT YET INDEXED
651 _aMedStar Washington Hospital Center
656 _aMedicine/Internal Medicine
657 _aJournal Article
700 _aDuong, Nikki
790 _aDuong N, Lee A, Lewis J
856 _uhttps://dx.doi.org/10.1136/bcr-2017-222373
_zhttps://dx.doi.org/10.1136/bcr-2017-222373
942 _cART
_dArticle
999 _c3112
_d3112