000			02834nam a22004337a 4500
008			180619s20182018 xxu||||| |||| 00| 0 eng d
022			_a1528-4042
024			_a10.1007/s11910-018-0839-1 [doi]
024			_a10.1007/s11910-018-0839-1 [pii]
040			_aOvid MEDLINE(R)
099			_a29721718
245			_aAn Up to Date Review of Pseudotumor Cerebri Syndrome. [Review]
251			_aCurrent Neurology & Neuroscience Reports. 18(6):33, 2018 May 02.
252			_aCurr Neurol Neurosci Rep. 18(6):33, 2018 May 02.
253			_aCurrent neurology and neuroscience reports
260			_c2018
260			_fFY2018
266			_d2018-06-19
520			_aPURPOSE OF REVIEW: Idiopathic intracranial hypertension (IIH), pseudotumor cerebri syndrome (PTCS), and benign intracranial hypertension are all terms that have been used for a neurologic syndrome consisting of elevated intracranial pressure (ICP), headache and vision loss without mass lesion or underlying infection or malignancy. In this review article, categorization, diagnostic criteria, symptom management strategies, and disease treatment options for pseudotumor cerebri syndrome will be discussed.
520			_aRECENT FINDINGS: The Idiopathic Intracranial Hypertension Treatment Trial has now proven that acetazolamide should be the first line therapy in primary PTCS, but other treatment options exist in patients who cannot tolerate acetazolamide or in selected cases, which requires surgical intervention for PTCS which acutely threatens vision. Headache has also been shown to require focused treatment beyond therapies that lower ICP, specifically targeting coexistent primary headache disorders and medication overuse. Advances in treatment and diagnostic modalities have improved understanding of PTCS types and their treatment. The pathophysiology of primary PTCS, however, remains incompletely understood, but continued evaluation of cerebrospinal fluid flow dynamics, aquaporins, hormones, natriuretic peptides, and the link with female gender and obesity may lead to future answers.
546			_aEnglish
650			_a*Pseudotumor Cerebri/di [Diagnosis]
650			_a*Pseudotumor Cerebri/th [Therapy]
650			_aAnimals
650			_aHumans
650			_aIntracranial Hypertension/di [Diagnosis]
650			_aIntracranial Hypertension/pp [Physiopathology]
650			_aIntracranial Hypertension/th [Therapy]
650			_aPseudotumor Cerebri/pp [Physiopathology]
650			_aSyndrome
651			_aMedStar Washington Hospital Center
656			_aNeurology
657			_aJournal Article
657			_aReview
700			_aBurkett, John Glenn
790			_aAilani J, Burkett JG
856			_uhttps://dx.doi.org/10.1007/s11910-018-0839-1 _zhttps://dx.doi.org/10.1007/s11910-018-0839-1
942			_cART _dArticle
999			_c3428 _d3428