| 000 | 02540nam a22004457a 4500 | ||
|---|---|---|---|
| 008 | 180706s20182018 xxu||||| |||| 00| 0 eng d | ||
| 022 | _a0007-5027 | ||
| 024 | _a10.1093/labmed/lmy025 [doi] | ||
| 024 | _a5036164 [pii] | ||
| 040 | _aOvid MEDLINE(R) | ||
| 099 | _a29897485 | ||
| 245 | _aSevere Underestimation of Serum Na following IVIG Treatment. | ||
| 251 | _aLaboratory Medicine. 49(4):372-376, 2018 Oct 11. | ||
| 252 | _aLab Med. 49(4):372-376, 2018 Oct 11. | ||
| 253 | _aLaboratory medicine | ||
| 260 | _c2018 | ||
| 260 | _fFY2019 | ||
| 266 | _d2018-07-06 | ||
| 269 | _fFY2018 | ||
| 520 | _aCurrent chemistry analyzers measure ion concentration using ion- selective electrodes; however, may differ in the specific technology at the bedside versus the central laboratory. Instruments utilized for point-of-care testing (POCT) at the bedside use direct ion-selective electrodes, whereas central-laboratory analyzers use indirect ion-selective electrodes. Under most circumstances, these instruments will deliver the same result; however, various substances can cause interferences in one or the other. An 18-year-old Hispanic woman with a history of immune thrombocytopenic purpura (ITP) presented at Children's National Medical Center (CNMC) with a severe headache and required intravenous immunoglobulin (IVIG) therapy. Because a discrepancy developed between her point-of-care and central-laboratory sodium values, another instrument was used to retest the central-laboratory plasma specimens. The results were more in agreement with those from the point-of-care instrument and revealed a unique interference in sodium measurement related to IVIG use. | ||
| 546 | _aEnglish | ||
| 650 | _a*Immunoglobulins, Intravenous/tu [Therapeutic Use] | ||
| 650 | _a*Purpura, Thrombocytopenic, Idiopathic/bl [Blood] | ||
| 650 | _a*Purpura, Thrombocytopenic, Idiopathic/dt [Drug Therapy] | ||
| 650 | _a*Sodium/bl [Blood] | ||
| 650 | _aAdolescent | ||
| 650 | _aDiagnostic Errors | ||
| 650 | _aFemale | ||
| 650 | _aHumans | ||
| 650 | _aPurpura, Thrombocytopenic, Idiopathic/di [Diagnosis] | ||
| 650 | _aPurpura, Thrombocytopenic, Idiopathic/pp [Physiopathology] | ||
| 650 | _aReproducibility of Results | ||
| 651 | _aMedStar Washington Hospital Center | ||
| 656 | _aPathology | ||
| 657 | _aJournal Article | ||
| 700 | _aVirk, Mrigender S | ||
| 790 | _aDean NP, Virk MS, Wong ECC | ||
| 856 |
_uhttps://dx.doi.org/10.1093/labmed/lmy025 _zhttps://dx.doi.org/10.1093/labmed/lmy025 |
||
| 942 |
_cART _dArticle |
||
| 999 |
_c3512 _d3512 |
||