000 02147nam a22003737a 4500
008 190108s20182018 xxu||||| |||| 00| 0 eng d
022 _a0003-4894
024 _a10.1177/0003489418818579 [doi]
040 _aOvid MEDLINE(R)
099 _a30556399
245 _aIntralesional Cidofovir for Treatment of Acyclovir-Resistant Laryngeal Herpes Manifesting as Supraglottic Mass.
251 _aAnnals of Otology, Rhinology & Laryngology. :3489418818579, 2018 Dec 17
252 _aAnn Otol Rhinol Laryngol. :3489418818579, 2018 Dec 17
253 _aThe Annals of otology, rhinology, and laryngology
260 _c2018
260 _fFY2019
265 _saheadofprint
266 _d2019-01-08
501 _aAvailable online from MWHC library: 1998 - 2008, Available in print through MWHC library: 1999 - 2008
520 _aCASE PRESENTATION:: We report a case of bulky, obstructive supraglottic and glottic herpes virus laryngitis that presented with dysphonia, dysphagia, and airway complaints resistant to acyclovir analogues that was treated effectively with intralesional cidofovir injection.
520 _aCONCLUSIONS:: Our promising initial response suggests a potential novel treatment for this unusual condition.
520 _aINTRODUCTION:: Laryngopharyngeal herpes simplex virus infection is rare and presents typically in the supraglottis. Findings on presentation can range from small mucosal lesions to fungating obstructive masses mimicking neoplasm. Laryngopharyngeal herpes is a medically treated disease.
520 _aMETHODS:: Individual case with treatment adapted from other case report.
520 _aOBJECTIVES:: Identify potential treatment in cases that are refractory to antiviral medications.
546 _aEnglish
650 _aIN PROCESS -- NOT YET INDEXED
651 _aMedStar Washington Hospital Center
656 _aMedicine/Infectious Diseases
657 _aJournal Article
700 _aMathur, Anisha
790 _aDhillon VK, Kumar PN, Mathur A, Yang CQ
856 _uhttps://dx.doi.org/10.1177/0003489418818579
_zhttps://dx.doi.org/10.1177/0003489418818579
942 _cART
_dArticle
999 _c3970
_d3970