000			02494nam a22003617a 4500
008			190108s20182018 xxu||||| |||| 00| 0 eng d
022			_a2328-8957
024			_a10.1093/ofid/ofy265 [doi]
024			_aofy265 [pii]
024			_aPMC6280940 [pmc]
040			_aOvid MEDLINE(R)
099			_a30539033
245			_aPredictors of Surgical Intervention in Dialysis Patients With Infective Endocarditis.
251			_aOpen Forum Infectious Diseases. 5(11):ofy265, 2018 Nov.
252			_aOpen forum infect. dis.. 5(11):ofy265, 2018 Nov.
253			_aOpen forum infectious diseases
260			_c2018
260			_fFY2019
265			_sepublish
266			_d2019-01-08
520			_aBackground: The use of valve surgery for infective endocarditis (IE) in end-stage renal disease (ESRD) patients may be different than in the general population. We assessed predictors of early surgery in ESRD patients with IE.
520			_aConclusions: Among ESRD patients with IE, most surgical indications are not predictive of early surgery.
520			_aMethods: We conducted a retrospective cohort study among dialysis patients with left-sided IE between 2005 and 2015. Indications for surgery were based on current endocarditis guidelines. Patients were categorized as early valve replacement surgery or delayed/no surgery. We used logistic regression to determine independent predictors of early surgery.
520			_aResults: Among 229 patients, 67 (29.3%) underwent early surgery. New congestive heart failure was the only high level of evidence indication independently associated with early surgery (odds ratio [OR], 12.1; 95% confidence interval [CI], 3.4-43.6). Transfer from outside hospital (OR, 5.4; 95% CI, 2.2-13.3), valve rupture (OR, 6.9; 95% CI, 2.6-17.9), coagulase-negative staphylococcus etiology (OR, 3.8; 95% CI, 1.4-10.6), and presence of any low level of evidence indication (OR, 5.9; 95% CI, 2.2-15.5) predicted early surgery. Preexisting valve disease (OR, 0.31; 95% CI, 0.12-0.82) and surgical contraindications (OR, 0.05; 95% CI, 0.005-0.4) predicted nonsurgical treatment.
546			_aEnglish
650			_aIN PROCESS -- NOT YET INDEXED
651			_aMedStar Heart & Vascular Institute
657			_aJournal Article
700			_aThourani, Vinod H
790			_aJacob JT, Robichaux C, Thourani VH, Walsh VL, Woller Iii JA
856			_uhttps://dx.doi.org/10.1093/ofid/ofy265 _zhttps://dx.doi.org/10.1093/ofid/ofy265
942			_cART _dArticle
999			_c3994 _d3994