000 02574nam a22003497a 4500
008 191014s20192019 xxu||||| |||| 00| 0 eng d
022 _a2210-2612
024 _a10.1016/j.ijscr.2019.09.005 [doi]
024 _aS2210-2612(19)30504-8 [pii]
040 _aOvid MEDLINE(R)
099 _a31563667
245 _aPeritoneal carcinomatosis of unknown primary site may be an undiagnosed appendiceal adenocarcinoma. A case series.
251 _aInternational Journal of Surgery Case Reports. 63:65-68, 2019 Sep 18.
252 _aInt J Surg Case Rep. 63:65-68, 2019 Sep 18.
253 _aInternational journal of surgery case reports
260 _c2019
260 _fFY2020
265 _saheadofprint
266 _d2019-10-14
520 _aBACKGROUND: Peritoneal carcinomatosis is sometimes diagnosed by cytology or by biopsy, but routine radiologic and endoscopic workup may not reveal a primary site. This clinical condition is called adenocarcinoma of unknown primary site.
520 _aCONCLUSIONS: Peritoneal carcinomatosis of unknown primary site may be caused by an occult appendiceal adenocarcinoma. This error in diagnosis may lead to suboptimal treatment. Surgical exploration to visualize a normal appendix should occur prior to making a definitive diagnosis of peritoneal carcinomatosis of unknown primary site. Copyright (c) 2019 The Author(s). Published by Elsevier Ltd.. All rights reserved.
520 _aMETHODS: The clinical findings of two patients with adenocarcinoma of unknown primary site were presented and the implications for management of similar patients were suggested.
520 _aRESULTS: The patient had the diagnosis of adenocarcinoma of unknown primary site made when cancer was discovered at the time of umbilical hernia repair or laparoscopy. Radiologic and endoscopic tests were not definitive in providing the primary site for the malignancy. Exploratory laparotomy was performed which revealed an appendiceal mucinous adenocarcinoma as the cause of the peritoneal carcinomatosis. Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) were used at the time of the exploratory laparotomy to treat the appendiceal adenocarcinoma with peritoneal metastases.
546 _aEnglish
650 _aIN PROCESS -- NOT YET INDEXED
651 _aWashington Cancer Institute
657 _aJournal Article
700 _aSugarbaker, Paul H
790 _aSugarbaker PH
856 _uhttps://dx.doi.org/10.1016/j.ijscr.2019.09.005
_zhttps://dx.doi.org/10.1016/j.ijscr.2019.09.005
942 _cART
_dArticle
999 _c4651
_d4651