000			02647nam a22003497a 4500
008			200826s20202020 xxu||||| |||| 00| 0 eng d
022			_a2168-8184
024			_a10.7759/cureus.8004 [doi]
024			_aPMC7279683 [pmc]
040			_aOvid MEDLINE(R)
099			_a32528746
245			_aRegadenoson Cardiac Stress Test-Induced Takotsubo Cardiomyopathy: A Case Report.
251			_aCureus. 12(5):e8004, 2020 May 07.
252			_aCureus. 12(5):e8004, 2020 May 07.
253			_aCureus
260			_c2020
260			_fFY2020
265			_sepublish
266			_d2020-08-26
520			_aA 79-year-old female presented with acute left-sided chest pain with shortness of breath; she was afebrile and vitally stable. She had a mildly elevated troponin (0.11 ng/mL). Her N terminal pro B-type natriuretic peptide (NT-proBNP) was 7053 pg/mL and electrocardiography (ECG) showed nonspecific ST, T wave changes. Transthoracic echocardiogram (TTE) revealed an ejection fraction (EF) of 65-70%. She was diagnosed with a non-ST elevation myocardial infarction (NSTEMI) and underwent a nuclear stress test, which was negative for ischemia with no left ventricular motion abnormality and an EF of 73%. The patient developed acute respiratory failure following the Lexiscan (Astellas Pharma US, Northbrook, IL) and had to be intubated. A chest X-ray showed pulmonary edema, and transesophageal echocardiography (TEE) revealed a severely reduced EF of 25% with a new anterior wall motion abnormality. Left heart catheterization showed no significant coronary artery disease. Ventriculogram revealed a significantly reduced EF of 30% with apical akinesia. These findings were compatible with myocardial infarction with non-obstructive coronary arteries (MINOCA), likely secondary to regadenoson, which presented like takotsubo cardiomyopathy (TCM). Her condition gradually improved and the follow-up echo revealed baseline EF without symptoms of heart failure. In conclusion, takotsubo cardiomyopathy can be a potential complication from Lexiscan and can present as new-onset heart failure after the stress test. Copyright (c) 2020, Farid et al.
546			_aEnglish
650			_aIN PROCESS -- NOT YET INDEXED
651			_aMedStar Heart & Vascular Institute
651			_aMedStar Washington Hospital Center
656			_aMedicine/General Internal Medicine
657			_aCase Reports
700			_aFarid, Saira
700			_aGarcia-Garcia, Hector M
790			_aAhsan M, Farid S, Garcia-Garcia HM
856			_uhttps://dx.doi.org/10.7759/cureus.8004 _zhttps://dx.doi.org/10.7759/cureus.8004
942			_cART _dArticle
999			_c5352 _d5352