000			02697nam a22004097a 4500
008			200902s20202020 xxu||||| |||| 00| 0 eng d
022			_a2054-4774
024			_a10.1136/bmjgast-2020-000466 [doi]
024			_abmjgast-2020-000466 [pii]
024			_aPMC7422689 [pmc]
040			_aOvid MEDLINE(R)
099			_a32788199
245			_aBlack esophagus: a syndrome of acute esophageal necrosis associated with active alcohol drinking.
251			_aBMJ Open Gastroenterology. 7(1), 2020 Aug.
252			_aBMJ Open Gastroenterol. 7(1), 2020 Aug.
253			_aBMJ open gastroenterology
260			_c2020
260			_fFY2021
265			_sppublish
266			_d2020-09-02
520			_aBlack esophagus, also known as acute esophageal necrosis (AEN) syndrome, is a rare entity characterized by patchy or diffuse circumferential black pigmentation of the esophageal mucosa from ischemic necrosis. It may present with life-threatening upper gastrointestinal hemorrhage resulting in high mortality in immunocompromised patients. Advanced age with multiple comorbidities compounded with compromised hemodynamic states are poor prognostic factors. Findings on laboratory work-up and radiological imaging are non-specific. After initial resuscitation, endoscopic evaluation and histological examination of esophageal biopsy are diagnostic. Early recognition and aggressive resuscitation are the fundamental principles for the management of AEN and better outcome of the disease. We report a case of a 56-year-old woman with diabetes mellitus, gastro-esophageal reflux disease, and active alcohol binging who presented with hematemesis and acute epigastric pain due to AEN. This case illustrates a rare etiology of AEN due to active alcohol drinking, which may be overlooked. Physician awareness about this etiology is important as early recognition and timely management may improve survival. Copyright (c) Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
546			_aEnglish
650			_aIN PROCESS -- NOT YET INDEXED
651			_aMedStar Health Baltimore Residents
651			_aMedStar Union Memorial Hospital
656			_aMedicine
657			_aJournal Article
700			_aChaudhary, Fizah S
700			_aFarooqi, Rehan
700			_aNaqvi, Haider A
700			_aSaleh, Nahar
700			_aSiddiqi, Anees
700			_aYousaf, Muhammad Nadeem
790			_aChaudhary FS, Farooqi R, Naqvi HA, Saleh N, Siddiqi A, Yousaf MN
856			_uhttps://dx.doi.org/10.1136/bmjgast-2020-000466 _zhttps://dx.doi.org/10.1136/bmjgast-2020-000466
942			_cART _dArticle
999			_c5473 _d5473