| 000 | 02556nam a22005057a 4500 | ||
|---|---|---|---|
| 008 | 200902s20202020 xxu||||| |||| 00| 0 eng d | ||
| 022 | _a1757-790X | ||
| 024 | _a10.1136/bcr-2020-236009 [doi] | ||
| 024 | _a13/7/e236009 [pii] | ||
| 024 | _aPMC7389772 [pmc] | ||
| 040 | _aOvid MEDLINE(R) | ||
| 099 | _a32723779 | ||
| 245 | _aIntermittent left bundle branch block and acute heart failure in trastuzumab-induced cardiotoxicity. | ||
| 251 | _aBMJ Case Reports. 13(7), 2020 Jul 28. | ||
| 252 | _aBMJ Case Rep. 13(7), 2020 Jul 28. | ||
| 252 | _zBMJ Case Rep. 13(7), 2020 Jul 28. | ||
| 253 | _aBMJ case reports | ||
| 260 | _c2020 | ||
| 260 | _fFY2021 | ||
| 265 | _sepublish | ||
| 265 | _sepublish | ||
| 266 | _d2020-09-02 | ||
| 268 | _aBMJ Case Reports. 13(7), 2020 Jul 28. | ||
| 520 | _aA 70-year-old woman with HER2+/ER+ breast cancer on adjuvant trastuzumab therapy without a history of cardiovascular disease presented with respiratory failure from influenza and was found to have intermittent left bundle branch block (LBBB) with new onset systolic heart failure. Her course was complicated by polymorphic ventricular tachycardia and recurrent chest pain. Significant investigations included a normal cardiac MRI and cardiac catheterisation with unobstructed coronaries. It was determined that the aetiology of her heart failure was trastuzumab-induced cardiotoxicity after comprehensive workup. This case highlights an uncommon presentation of LBBB and the steps taken to diagnose a rare cardiomyopathy. Copyright (c) BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ. | ||
| 546 | _aEnglish | ||
| 650 | _a*Antineoplastic Agents, Immunological/ae [Adverse Effects] | ||
| 650 | _a*Bundle-Branch Block/ci [Chemically Induced] | ||
| 650 | _a*Heart Failure, Systolic/ci [Chemically Induced] | ||
| 650 | _a*Trastuzumab/ae [Adverse Effects] | ||
| 650 | _aAged | ||
| 650 | _aBreast Neoplasms/ch [Chemistry] | ||
| 650 | _aBreast Neoplasms/dt [Drug Therapy] | ||
| 650 | _aBundle-Branch Block/pp [Physiopathology] | ||
| 650 | _aCardiotoxicity/co [Complications] | ||
| 650 | _aElectrocardiography | ||
| 650 | _aFemale | ||
| 650 | _aHumans | ||
| 651 | _aMedStar Washington Hospital Center | ||
| 656 | _aMedicine/Internal Medicine | ||
| 657 | _aJournal Article | ||
| 700 | _aMasson, Ravi | ||
| 790 | _aBakhshi H, Haddad TM, Masson R | ||
| 856 |
_uhttps://dx.doi.org/10.1136/bcr-2020-236009 _zhttps://dx.doi.org/10.1136/bcr-2020-236009 |
||
| 942 |
_cART _dArticle |
||
| 999 |
_c5487 _d5487 |
||