000			02130nam a22003257a 4500
008			201229s20202020 xxu||||| |||| 00| 0 eng d
022			_a1548-825X
040			_aOvid MEDLINE(R)
099			_a33044154
245			_aCurrent Biopsy Methods for Primary Musculoskeletal Lymphoma: A Retrospective Multicenter Review.
252			_aJ Surg Orthop Adv. 29(3):149-153, 2020.
253			_aJournal of surgical orthopaedic advances
260			_c2020
260			_fFY2021
265			_sppublish
266			_d2020-12-29
520			_aPrimary musculoskeletal lymphoma often requires multiple biopsies for tissue confirmation. This challenge is understood by specialists but has not been specifically quantified. One-hundred-eighteen biopsies performed in 100 cases of primary musculoskeletal lymphoma was performed. Demographics, tumor location and the method and performer of biopsy were recorded. Pearson chi-square and analysis of variance (ANOVA) statistics were used to compare rates of diagnostic yield, time to diagnosis and the presence of crush artifact based on method of biopsy, imaging, performer and tumor location. Diagnostic yield of initial biopsy is 82%. Open biopsy is associated with a higher yield compared to percutaneous techniques (p = 0.005). Biopsies performed by the treating surgeon had a higher yield compared to other practitioners (p = 0.035). Musculoskeletal lymphomas are a greater diagnostic challenge compared to other lesions. A higher index of suspicion and more aggressive sampling procedure may be necessary to establish this diagnosis. (Journal of Surgical Orthopaedic Advances 29(3):149-153, 2020).
546			_aEnglish
650			_aIN PROCESS -- NOT YET INDEXED
651			_aMedStar Franklin Square Medical Center
656			_aOrthopaedic Oncology, National Center for Bone and Soft Tissue Tumors
656			_aOrthopaedic Onology
657			_aJournal Article
700			_aAboulafia, Albert
700			_aFrassica, Frank J
700			_aSin, Alex
700			_aWallace, Matthew T
790			_aAboulafia AJ, Frassica FJ, Sin A, Wallace MT
942			_cART _dArticle
999			_c5688 _d5688