000 02921nam a22004697a 4500
008 201229s20212021 xxu||||| |||| 00| 0 eng d
022 _a0013-726X
024 _a10.1055/a-1276-0219 [doi]
040 _aOvid MEDLINE(R)
099 _a33096576
245 _aImpact of prior treatment on feasibility and outcomes of Zenker's peroral endoscopic myotomy (Z-POEM).
251 _aEndoscopy. 53(7):722-726, 2021 07.
252 _aEndoscopy. 53(7):722-726, 2021 07.
252 _zEndoscopy. 2020 Oct 23
253 _aEndoscopy
260 _c2021
260 _fFY2022
265 _saheadofprint
265 _sppublish
266 _d2020-12-29
268 _aEndoscopy. 2020 Oct 23
269 _fFY2021
501 _aAvailable online through MWHC library: 1999 - 2010, Available in print through MWHC library: 1999 - 2006
520 _aBACKGROUND: Zenker's peroral endoscopic myotomy (Z-POEM) is a novel procedure for the management of symptomatic Zenker's diverticulum. This study aims to report the technical feasibility and outcomes of Z-POEM in the management of Zenker's diverticulum after prior failed interventions.
520 _aCONCLUSION: Z-POEM is feasible, safe, and effective in the majority of patients with recurrent symptoms after prior surgical or endoscopic interventions. Copyright Thieme. All rights reserved.
520 _aMETHODS: Patients with persistent or recurrent symptoms after prior endoscopic and/or surgical intervention for Zenker's diverticulum were retrospectively included. The primary outcome was clinical success, defined as complete or near complete resolution of dysphagia (dysphagia score of 0 or 1) without the need for repeat endoscopic or surgical intervention during follow-up.
520 _aRESULTS: Z-POEM was technically successful in 30/32 patients (93.8 %). Clinical success was achieved in 29/30 patients (96.7 %), and Z-POEM significantly reduced the median (interquartile range [IQR]) dysphagia score of patients from 2 (1 - 2) to 0 (0) (P < 0.001) over a median duration of follow up of 166 days (IQR 39 - 566). Four patients (12.5 %) had adverse events (two inadvertent mucosotomies and two leaks found on post-procedural esophagrams).
546 _aEnglish
650 _a*Myotomy
650 _a*Zenker Diverticulum
650 _aFeasibility Studies
650 _aHumans
650 _aRetrospective Studies
650 _aTreatment Outcome
650 _aZenker Diverticulum/su [Surgery]
651 _aMedStar Union Memorial Hospital
657 _aJournal Article
700 _aSanaei, OmidKW - Medicine
790 _aAl-Ghamdi SS, Attaar M, Desai PN, Deshmukh A, Farha J, Ginsberg GG, Ichkhanian Y, Jovani M, Khashab MA, Krishnan A, Mondragon OVH, Nieto J, Sanaei O, Saumoy M, Tantau A, Tantau M, Ujiki M
856 _uhttps://dx.doi.org/10.1055/a-1276-0219
_zhttps://dx.doi.org/10.1055/a-1276-0219
942 _cART
_dArticle
999 _c5868
_d5868