000			02710nam a22003497a 4500
008			201231s20202020 xxu||||| |||| 00| 0 eng d
022			_a0920-9964
024			_a10.1016/j.schres.2020.07.023 [doi]
024			_aS0920-9964(20)30416-3 [pii]
040			_aOvid MEDLINE(R)
099			_a33183948
245			_aSystematic review of racial disparities in clozapine prescribing.
251			_aSchizophrenia Research. 224:11-18, 2020 Oct.
252			_aSchizophr Res. 224:11-18, 2020 Oct.
253			_aSchizophrenia research
260			_c2020
260			_fFY2021
265			_sppublish
266			_d2020-12-31
520			_aCONCLUSION: The reasons for underutilization of clozapine in minority patients remain unclear. Various contributors can be categorized as: clinician-related factors (e.g. prescriber lack of experience), patient-related factors (e.g. distrust or suspicion of clinician), and institution-related factors (e.g. state operated facilities). Direct examination of these factors can help inform efforts to reduce clozapine prescription disparities. Copyright (c) 2020. Published by Elsevier B.V.
520			_aFINDINGS: 16 studies met our eligibility criteria. All studies reported clozapine underutilization in ethnic and racial minority patients when compared to their white counterparts. These findings remained consistent despite different time periods, designs, data set types, and after controlling for relevant covariates such as: length of hospital stay, institutional setting, and disease severity.
520			_aMETHODS: Electronic databases (MEDLINE, Embase, PsycINFO, Web of Science) were searched for directly relevant studies. Three independent reviewers selected studies: (1) of US samples; (2) directly addressed ethnic and/or racial disparities in prescribing of antipsychotic medications; (3) identified specific ethnic and/or racial groups (e.g. White, Blacks, Hispanics, non-Hispanic etc.); (4) reported clozapine prescription rates and (5) reported relevant covariates (i.e. gender, age, co-morbidities etc.).
520			_aOBJECTIVE: To conduct a systematic review of published evidence on clozapine prescribing disparities across racial and ethnic categories, estimate the size of these disparities, and assess possible causes to inform future monitoring and intervention.
546			_aEnglish
650			_aIN PROCESS -- NOT YET INDEXED
651			_aMedStar Medical Group
657			_aJournal Article
700			_aWilliams, J Corey
790			_aGlover J, Harowitz J, Srihari V, Tek C, Williams JC
856			_uhttps://dx.doi.org/10.1016/j.schres.2020.07.023 _zhttps://dx.doi.org/10.1016/j.schres.2020.07.023
942			_cART _dArticle
999			_c6011 _d6011