000 | 03542nam a22005057a 4500 | ||
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008 | 210217s20212021 xxu||||| |||| 00| 0 eng d | ||
022 | _a0090-3493 | ||
024 | _a00003246-202102000-00002 [pii] | ||
024 | _a10.1097/CCM.0000000000004783 [doi] | ||
040 | _aOvid MEDLINE(R) | ||
099 | _a33438970 | ||
245 | _aNosocomial Infection. [Review] | ||
251 | _aCritical Care Medicine. 49(2):169-187, 2021 02 01. | ||
252 | _aCrit Care Med. 49(2):169-187, 2021 02 01. | ||
252 | _zCrit Care Med. 49(2):169-187, 2021 Feb 01. | ||
253 | _aCritical care medicine | ||
260 | _c2021 | ||
260 | _fFY2021 | ||
265 | _sppublish | ||
266 | _d2021-02-17 | ||
268 | _aCritical Care Medicine. 49(2):169-187, 2021 Feb 01. | ||
501 | _aAvailable online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006 | ||
520 | _aCONCLUSIONS: Nosocomial infections are an important determinant of outcome for patients in the ICU setting. Systematic research aimed at improving the prevention and treatment of nosocomial infections is still needed. Copyright (c) 2021 by the Society of Critical Care Medicine and Wolters Kluwer Health, Inc. All Rights Reserved. | ||
520 | _aDATA EXTRACTION AND DATA SYNTHESIS: Nosocomial infections in the ICU setting are evolving in multiple domains including etiologic pathogens plus novel or emerging pathogens, prevalence, host risk factors, antimicrobial resistance, interactions of the host microbiome with nosocomial infection occurrence, and understanding of pathogenesis and prevention strategies. Increasing virulence and antimicrobial resistance of nosocomial infections mandate increasing efforts toward their prevention. | ||
520 | _aDATA SOURCES AND STUDY SELECTION: We searched PubMed and OVID for peer-reviewed literature dealing with nosocomial infections in the critically ill, as well as the websites of government agencies involved with the reporting and prevention of nosocomial infections. Search terms included nosocomial infection, antibiotic resistance, microbiome, antibiotics, and intensive care. | ||
520 | _aOBJECTIVE: The first 70 years of critical care can be considered a period of "industrial revolution-like" advancement in terms of progressing the understanding and care of critical illness. Unfortunately, like the industrial revolution's impact on the environment, advancing ICU care of increasingly elderly, immunosuppressed, and debilitated individuals has resulted in a greater overall burden and complexity of nosocomial infections within modern ICUs. Given the rapid evolution of nosocomial infections, the authors provide an updated review. | ||
546 | _aEnglish | ||
650 | _a*Critical Care/og [Organization & Administration] | ||
650 | _a*Critical Illness/th [Therapy] | ||
650 | _a*Cross Infection/th [Therapy] | ||
650 | _a*Drug Resistance, Bacterial | ||
650 | _aAnti-Infective Agents, Local/tu [Therapeutic Use] | ||
650 | _aCross Infection/pc [Prevention & Control] | ||
650 | _aHumans | ||
650 | _aIntensive Care Units/og [Organization & Administration] | ||
650 | _aRisk Assessment | ||
650 | _aRisk Factors | ||
651 | _aMedStar Washington Hospital Center | ||
656 | _aMedicine/Pulmonary-Critical Care | ||
657 | _aJournal Article | ||
700 | _aShorr, Andrew F | ||
790 | _aKollef MH, Martin-Loeches I, Micek ST, Shorr AF, Torres A | ||
856 |
_uhttps://dx.doi.org/10.1097/CCM.0000000000004783 _zhttps://dx.doi.org/10.1097/CCM.0000000000004783 |
||
942 |
_cART _dArticle |
||
999 |
_c6114 _d6114 |