000			03566nam a22005897a 4500
008			210310s20212021 xxu||||| |||| 00| 0 eng d
022			_a1557-2625
024			_a10.3122/jabfm.2021.S1.200464 [doi]
024			_a34/Supplement/S127 [pii]
040			_aOvid MEDLINE(R)
099			_a33622827
245			_aDevelopment and Validation of the COVID-NoLab and COVID-SimpleLab Risk Scores for Prognosis in 6 US Health Systems.
251			_aJournal of the American Board of Family Medicine: JABFM. 34(Suppl):S127-S135, 2021 Feb.
252			_aJ Am Board Fam Med. 34(Suppl):S127-S135, 2021 Feb.
252			_zJ Am Board Fam Med. 34(Suppl):S127-S135, 2021 Feb.
253			_aJournal of the American Board of Family Medicine : JABFM
260			_c2021
260			_fFY2021
265			_sppublish
266			_d2021-03-10
268			_aJournal of the American Board of Family Medicine: JABFM. 34(Suppl):S127-S135, 2021 Feb.
501			_aAvailable online from MWHC library: 2001 - present
520			_aCONCLUSIONS: Because they use simple, readily available predictors, developed risk scores have potential applicability in the outpatient setting but require prospective validation before use. (c) Copyright 2021 by the American Board of Family Medicine.
520			_aMETHODS: We gathered clinical and initial laboratory variables on consecutive inpatients with COVID-19 who had either died or been discharged alive at 6 US health centers. Logistic regression was used to develop a predictive model using no laboratory values (COVID-NoLab) and one adding tests available in many outpatient settings (COVID-SimpleLab). The models were converted to point scores and their accuracy evaluated in an internal validation group.
520			_aPURPOSE: Develop and validate simple risk scores based on initial clinical data and no or minimal laboratory testing to predict mortality in hospitalized adults with COVID-19.
520			_aRESULTS: We identified 1340 adult inpatients with complete data for nonlaboratory parameters and 741 with complete data for white blood cell (WBC) count, differential, c-reactive protein (CRP), and serum creatinine. The COVID-NoLab risk score includes age, respiratory rate, and oxygen saturation and identified risk groups with 0.8%, 11.4%, and 40.4% mortality in the validation group (AUROCC = 0.803). The COVID-SimpleLab score includes age, respiratory rate, oxygen saturation, WBC, CRP, serum creatinine, and comorbid asthma and identified risk groups with 1.0%, 9.1%, and 29.3% mortality in the validation group (AUROCC = 0.833).
546			_aEnglish
650			_a*COVID-19/di [Diagnosis]
650			_a*Decision Support Systems, Clinical/st [Standards]
650			_a*Risk Assessment/mt [Methods]
650			_aAdult
650			_aAged
650			_aAged, 80 and over
650			_aCOVID-19/mo [Mortality]
650			_aFemale
650			_aHumans
650			_aMale
650			_aMiddle Aged
650			_aPandemics
650			_aPrognosis
650			_aRisk Factors
650			_aSARS-CoV-2
650			_aUnited States/ep [Epidemiology]
651			_aMedStar Washington Hospital Center
656			_aEmergency Medicine
657			_aJournal Article
700			_aGoyal, Munish
700			_aMaloy, Kevin
790			_aBarrett B, Cai X, Ebell MH, Goyal M, Krist A, Lennon R, Mainous AG 3rd, Maloy K, Tarn DM, Tuan WJ, Zgierska AE
856			_uhttps://dx.doi.org/10.3122/jabfm.2021.S1.200464 _zhttps://dx.doi.org/10.3122/jabfm.2021.S1.200464
942			_cART _dArticle
999			_c6232 _d6232