000			02683nam a22003257a 4500
008			210310s20212021 xxu||||| |||| 00| 0 eng d
022			_a2168-8184
024			_a10.7759/cureus.13516 [doi]
024			_aPMC7904504 [pmc]
040			_aOvid MEDLINE(R)
099			_a33654643
245			_aSitus Inversus Totalis in the Neonatal Setting.
251			_aCureus. 13(2):e13516, 2021 Feb 23.
252			_aCureus. 13(2):e13516, 2021 Feb 23.
253			_aCureus
260			_c2021
260			_fFY2021
265			_sepublish
266			_d2021-03-10
520			_aSitus inversus totalis (SIT) is a rare condition of complete inversion and mirroring of normal human anatomy. The incidence is approximately 1 in 8,000 to 1 in 25,000 live births. SIT is inherited in an autosomal recessive pattern and is associated with multiple gene mutations. It is also commonly seen in a condition known as primary ciliary dyskinesia. A 39-year-old pregnant woman presented to the Labor and Delivery unit to rule out pre-eclampsia due to high blood pressure recordings in the office setting. The infant was delivered preterm at 36 weeks gestation via spontaneous vaginal delivery. The infant presented with symptoms of respiratory distress. The newborn was transferred to the neonatal intensive care unit (NICU) for further work-up and to rule in/rule out an etiology known as Wet Lung. Upon retrieving a chest X-ray for the newborn, the results demonstrated situs inversus totalis. The newborn was transferred to a level III NICU for further management and work-up for other potential etiologies. Situs inversus totalis was not seen on prenatal work-up. In summary, situs inversus totalis is a rare condition which can be associated with other detrimental conditions. In the future, if situs inversus totalis is detected in utero, patients should be instructed to deliver in a setting in which any possible etiology can be accommodated. Pediatricians should follow these infants closely and with caution as common presentations may be obscured due to complete inversion of normal human anatomy. It is also important to screen these infants for other etiologies which may present in later developmental stages such as bronchiectasis and respiratory infections. Copyright (c) 2021, Devera et al.
546			_aEnglish
650			_aIN PROCESS -- NOT YET INDEXED
651			_aMedStar Harbor Hospital
657			_aCase Reports
700			_aTaymoorian, Hovik T
700			_aYap, Laurel G
790			_aDevera J, Licandro F, Ramos J, Taymoorian HT, Yap LG
856			_uhttps://dx.doi.org/10.7759/cureus.13516 _zhttps://dx.doi.org/10.7759/cureus.13516
942			_cART _dArticle
999			_c6242 _d6242