000			02549nam a22003857a 4500
008			210628s20212021 xxu||||| |||| 00| 0 eng d
022			_a0022-4790
024			_a10.1002/jso.26520 [doi]
040			_aOvid MEDLINE(R)
099			_a33961696
245			_aPeritoneal cytology as an indicator of peritoneal metastases in colorectal cancer.
251			_aJournal of Surgical Oncology. 2021 May 07
252			_aJ Surg Oncol. 2021 May 07
253			_aJournal of surgical oncology
260			_c2021
260			_fFY2021
260			_p2021 May 07
265			_saheadofprint
266			_d2021-06-28
520			_aBACKGROUND: In the management of peritoneal metastases from colon and rectal cancer, the most favorable results are reported with an aggressive combined treatment on patients who have a small extent of the disease. A test to detect occult peritoneal metastases would greatly facilitate the management of this component of colorectal dissemination.
520			_aCONCLUSION: Peritoneal cytology identified patients with mucinous histology and a large extent of disease but was consistently negative in patients who had a small extent of disease compatible with a favorable response to treatment. Copyright (c) 2021 Wiley Periodicals LLC.
520			_aMETHODS: Currently, the standard test by which to confirm the diagnosis of the peritoneal spread of colorectal cancer is peritoneal cytology. To study the utility of this test, we gathered information from patients with biopsy-proven peritoneal metastases. The clinical, histologic, and treatment-related features of these patients at the time of a cytoreductive surgery were statistically correlated with the results of the peritoneal cytology test.
520			_aRESULTS: Forty-nine patients with colorectal cancer peritoneal metastases and a peritoneal cytology determination at the time of a cytoreductive surgery were available for analysis. Twenty-eight patients (55.1%) had a positive test. Patients with a high peritoneal cancer index and mucinous histology were most likely to have positive peritoneal cytology.
546			_aEnglish
650			_aIN PROCESS -- NOT YET INDEXED
651			_aMedStar Washington Hospital Center
651			_aWashington Cancer Institute
656			_aPathology
657			_aJournal Article
700			_aDeng, Tom
700			_aSugarbaker, Paul H
790			_aChang D, Deng T, Sugarbaker PH
856			_uhttps://dx.doi.org/10.1002/jso.26520 _zhttps://dx.doi.org/10.1002/jso.26520
942			_cART _dArticle
999			_c6475 _d6475