000			04686nam a22007457a 4500
008			210726s20212021 xxu||||| |||| 00| 0 eng d
024			_a10.1016/j.mayocp.2021.03.038 [doi]
024			_aS0025-6196(21)00357-8 [pii]
040			_aOvid MEDLINE(R)
099			_a34272068
245			_aIn-Hospital Complications in Pregnant Women With Current or Historical Cancer Diagnoses.
251			_aMayo Clinic Proceedings. 96(11):2779-2792, 2021 11.
252			_aMayo Clin Proc. 96(11):2779-2792, 2021 11.
252			_zMayo Clin Proc. 2021 Jul 08
253			_aMayo Clinic proceedings
260			_c2021
260			_fFY2022
260			_p2021 Jul 08
265			_saheadofprint
265			_sppublish
266			_d2021-07-26
268			_aMayo Clinic Proceedings. 2021 Jul 08
269			_fFY2022
501			_aAvailable online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006
520			_aCONCLUSION: Women with a current or historical diagnosis of cancer at delivery have more comorbidities compared with women without cancer. Clinicians should communicate the risks of multisystem complications to these complex patients. Copyright (c) 2021 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.
520			_aMETHODS: We analyzed delivery hospitalizations with or without current or historical cancer between January 1, 2004, and December 31, 2014, from the US National Inpatient Sample database.
520			_aOBJECTIVE: To assess the temporal trends, characteristics and comorbidities, and in-hospital cardiovascular and obstetric complications and outcomes of pregnant women with current or historical cancer diagnosis at the time of admission for delivery.
520			_aRESULTS: We included 43,132,097 delivery hospitalizations with no cancer, 39,118 with current cancer, and 67,336 with historical diagnosis of cancer. The 5 most common types of current cancer were hematologic, thyroid, cervical, skin, and breast cancer. Women with current and historical cancer were older (29 years and 32 years vs 27 years) and incurred higher hospital costs ( _4131 and _4078 vs _3521) compared with women without cancer. Most of the cancer types were associated with preterm birth (hematologic: adjusted odds ratio [aOR], 1.48 [95% CI, 1.35 to 1.62]; cervical: aOR, 1.47 [95% CI, 1.32 to 1.63]; breast: aOR, 1.93 [95% CI, 1.72 to 2.16]). Current hematologic cancer was associated with the highest risk of peripartum cardiomyopathy (aOR, 12.19 [95% CI, 7.75 to 19.19]), all-cause mortality (aOR, 6.50 [95% CI, 2.22 to 19.07]), arrhythmia (aOR, 3.82 [95% CI, 2.04 to 7.15]), and postpartum hemorrhage (aOR, 1.31 [95% CI, 1.11 to 1.54]). Having a current or historical cancer diagnosis did not confer additional risk for stillbirth; however, metastases increased the risk of maternal mortality and preterm birth.
546			_aEnglish
650			_a*Neoplasms
650			_a*Obstetric Labor Complications
650			_a*Pregnancy Complications, Cardiovascular
650			_a*Pregnancy Complications, Neoplastic
650			_a*Premature Birth/ep [Epidemiology]
650			_aAdult
650			_aArrhythmias, Cardiac/di [Diagnosis]
650			_aArrhythmias, Cardiac/ep [Epidemiology]
650			_aCardiomyopathies/di [Diagnosis]
650			_aCardiomyopathies/ep [Epidemiology]
650			_aComorbidity
650			_aFemale
650			_aHumans
650			_aMaternal Mortality
650			_aNeoplasm Staging
650			_aNeoplasms/cl [Classification]
650			_aNeoplasms/ep [Epidemiology]
650			_aNeoplasms/pa [Pathology]
650			_aObstetric Labor Complications/di [Diagnosis]
650			_aObstetric Labor Complications/et [Etiology]
650			_aPregnancy
650			_aPregnancy Complications, Cardiovascular/di [Diagnosis]
650			_aPregnancy Complications, Cardiovascular/ep [Epidemiology]
650			_aPregnancy Complications, Neoplastic/di [Diagnosis]
650			_aPregnancy Complications, Neoplastic/ep [Epidemiology]
650			_aPregnancy Outcome/ep [Epidemiology]
650			_aRisk Assessment/sn [Statistics & Numerical Data]
650			_aSpatio-Temporal Analysis
650			_aUnited States/ep [Epidemiology]
651			_aMedStar Heart & Vascular Institute
657			_aJournal Article
700			_aBarac, Ana
790			_aBarac A, Chappell LC, Chew-Graham CA, Jordan KP, Lundberg GP, Maas AHEM, Mamas MA, Michos ED, Mohamed MO, Wu P
856			_uhttps://dx.doi.org/10.1016/j.mayocp.2021.03.038 _zhttps://dx.doi.org/10.1016/j.mayocp.2021.03.038
942			_cART _dArticle
999			_c6661 _d6661