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Bioprosthetic Aortic Valve Thrombosis: Definitions, Clinical Impact, and Management: A State-of-the-Art Review. [Review] - 2024

Available online from MWHC library: 2008 - present

Bioprosthetic aortic valve thrombosis is frequently detected after transcatheter and surgical aortic valve replacement due to advances in cardiac computed tomography angiography technology and standardized surveillance protocols in low-surgical-risk transcatheter aortic valve replacement trials. However, evidence is limited concerning whether subclinical leaflet thrombosis leads to clinical adverse events or premature structural valve deterioration. Furthermore, there may be net harm in the form of bleeding from aggressive antithrombotic treatment in patients with subclinical leaflet thrombosis. This review will discuss the incidence, mechanisms, diagnosis, and optimal management of bioprosthetic aortic valve thrombosis after transcatheter aortic valve replacement and bioprosthetic surgical aortic valve replacement.


English

ISSN: 1941-7640

Subjects--Topical Terms:
*Aortic Valve
*Bioprosthesis
*Fibrinolytic Agents
*Heart Valve Prosthesis
*Heart Valve Prosthesis Implantation
*Prosthesis Design
*Thrombosis
*Transcatheter Aortic Valve Replacement
Anticoagulants/ad [Administration & Dosage]
Anticoagulants/ae [Adverse Effects]
Anticoagulants/tu [Therapeutic Use]
Aortic Valve/dg [Diagnostic Imaging]
Aortic Valve/pp [Physiopathology]
Aortic Valve/su [Surgery]
Bioprosthesis/ae [Adverse Effects]
Fibrinolytic Agents/ad [Administration & Dosage]
Fibrinolytic Agents/ae [Adverse Effects]
Heart Valve Prosthesis Implantation/ae [Adverse Effects]
Heart Valve Prosthesis Implantation/is [Instrumentation]
Heart Valve Prosthesis/ae [Adverse Effects]
Humans
Incidence
Predictive Value of Tests
Risk Assessment
Risk Factors
Thrombosis/dg [Diagnostic Imaging]
Thrombosis/et [Etiology]
Thrombosis/th [Therapy]
Transcatheter Aortic Valve Replacement/ae [Adverse Effects]
Transcatheter Aortic Valve Replacement/is [Instrumentation]
Treatment Outcome--Automated

Subjects--Geographic Terms:
MedStar Heart & Vascular Institute
MedStar Washington Hospital Center

Index Terms--Occupation:
Advanced Cardiac Catheterization Research Fellowship
Interventional Cardiology Fellowship

Index Terms--Function:
Journal Article
Review