Evidence-based screening, clinical care and health education recommendations for Alaska Native peoples with prediabetes living in southcentral Alaska: findings from the Alaska EARTH follow-up study.

Evidence-based screening, clinical care and health education recommendations for Alaska Native peoples with prediabetes living in southcentral Alaska: findings from the Alaska EARTH follow-up study. - 2024

Available online through MWHC library: 2002 - present

Pre-diabetes (pre-DM) is a strong predictor of diabetes (DM) over time. This study investigated how much of the recent increase in pre-DM identified among Alaska Native (AN) peoples living in urban southcentral Alaska may be due to changes in diagnostic methods. We used clinical and demographic data collected at baseline between 2004 and 2006 and at follow-up collected between 2015 and 2017 from the urban southcentral Alaska Education and Research Towards Health (EARTH) cohort. We used descriptive statistics and logistic regression to explore differences in demographic and clinical variables among the identified pre-DM groups. Of 388 participants in the follow-up study, 243 had A1c levels indicating pre-DM with only 20 demonstrating pre-DM also by fasting blood glucose (FBG). Current smoking was the sole predictor for pre-DM by A1c alone while abdominal obesity and elevated FBG-predicted pre-DM by A1c+FBG. No participants had an elevated FBG without an A1c elevation. A substantial portion of the rise in pre-DM found among urban southcentral AN peoples in the EARTH follow-up study was due to the addition of A1c testing. Pre-DM by A1c alone should be used to motivate behavioural changes that address modifiable risk factors, including smoking cessation, physical activity and weight management.


English

1239-9736

PMC11064735 [pmc]


*Alaska Natives
*Prediabetic State
Adult
Aged
Alaska/ep [Epidemiology]
Blood Glucose/an [Analysis]
Female
Follow-Up Studies
Glycated Hemoglobin/an [Analysis]
Health Education/og [Organization & Administration]
Humans
Male
Mass Screening
Middle Aged
Prediabetic State/di [Diagnosis]
Prediabetic State/eh [Ethnology]
Risk Factors
Smoking/eh [Ethnology]
Smoking/ep [Epidemiology]--Curated


MedStar Health Research Institute


Journal Article
Research Support, N.I.H., Extramural

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