The relationship between subclinical atherosclerosis, non-high-density lipoprotein cholesterol, exercise, anddiet among male participants of the PACC Project. (Record no. 1323)

MARC details
000 -LEADER
fixed length control field 03935nam a22005417a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 130913s20122012 xxu||||| |||| 00| 0 eng dOvid Technologies
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 1876-4789
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 22385551
245 ## - TITLE STATEMENT
Title The relationship between subclinical atherosclerosis, non-high-density lipoprotein cholesterol, exercise, anddiet among male participants of the PACC Project.
251 ## - Source
Source Journal of Clinical Lipidology. 6(2):174-9, 2012 Mar-Apr.
252 ## - Abbreviated Source
Abbreviated source J. clin. lipidol.. 6(2):174-9, 2012 Mar-Apr.
253 ## - Journal Name
Journal name Journal of clinical lipidology
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2012
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Manufacturer FY2012
266 ## - Date added to catalog
Date added to catalog 2013-09-17
520 ## - SUMMARY, ETC.
Abstract BACKGROUND: Non-high-density lipoprotein (HDL) cholesterol is recommended as a secondary lipid goal treated initially with lifestyle modification. However, the relationship between non-HDL and subclinical atherosclerosis is unknown. We examined the independent relationships between coronary artery calcium (CAC), lipids including non-HDL, exercise, and diet among healthy male participants of the Prospective Army Coronary Calcium (PACC) Project.
520 ## - SUMMARY, ETC.
Abstract CONCLUSIONS: Non-HDL-C and exercise are independently predictive of the presence of subclinical CAC among healthy lower-risk middle-aged men. Copyright A 2012 National Lipid Association. All rights reserved.
520 ## - SUMMARY, ETC.
Abstract METHODS: Male participants from the PACC Project (n= 1637, mean age 42.8 years; no history of coronary heart disease) were studied. We used validated surveys to measure dietary quality and habitual physical exercise. Fasting lipid concentrations and other cardiovascular risk variables were measured. Subclinical atherosclerosis was detected with the use of electron beam computed tomography for CAC. Factors independently associated with the presence of any detectable CAC (CAC score > 0), including standard CV risk variables, non-HDL, exercise, and diet, were evaluated with the use of logistic regression.
520 ## - SUMMARY, ETC.
Abstract RESULTS: The mean Framingham risk score was 4.6 +/- 2.6%; CAC was present in 22.4%. Fasting lipid concentrations showed mean LDL-C 128 +/- 32 mg/dL, HDL-C 50 +/- 13 mg/dL, TG-C 130 +/- 86 mg/dL, and non-HDL-C 154 +/- 37 mg/dL. Men with CAC had significantly greater levels of LDL-C (135 vs 127 mg/dL), TG (148 vs 124 mg/dL), and non-HDL-C (164 vs 151 mg/dL) and less habitual physical activity (P= 0.006). There were nonsignificant trends between prevalent CAC, greater amounts of dietary fat intake, and lower HDL-C. In successive multivariable logistic regression models for the dependent variable CAC, only non-HDL-C (odds ratio [OR] 1.012 per mg/dL; 95% CI 1.002-1.023; P= .019) and age (OR 1.119 per year; 95% CI 1.063-1.178; P < .001) were independently associated with the presence of CAC, and exercise (OR 0.808; 95% CI 0.703-0.928; P= 0.003) was associated with the absence of CAC.
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Atherosclerosis/bl [Blood]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Calcium/me [Metabolism]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Cholesterol/bl [Blood]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Coronary Vessels/me [Metabolism]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Diet
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Exercise
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Military Personnel
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Adult
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Atherosclerosis/me [Metabolism]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Atherosclerosis/pp [Physiopathology]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Humans
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Logistic Models
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Male
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Middle Aged
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Prospective Studies
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Health Research Institute
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Heart & Vascular Institute
657 ## - INDEX TERM--FUNCTION
Medline publication type Clinical Trial
657 ## - INDEX TERM--FUNCTION
Medline publication type Journal Article
657 ## - INDEX TERM--FUNCTION
Medline publication type Research Support, Non-U.S. Gov't
657 ## - INDEX TERM--FUNCTION
Medline publication type Research Support, U.S. Gov't, Non-P.H.S.
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Simprini, Lauren A
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Taylor, Allen J
790 ## - Authors
All authors Rich M, Simprini LA, Taylor AJ, Villines TC
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="http://dx.doi.org/10.1016/j.jacl.2011.11.005">http://dx.doi.org/10.1016/j.jacl.2011.11.005</a>
Public note http://dx.doi.org/10.1016/j.jacl.2011.11.005
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
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              09/17/2013   22385551 22385551 09/17/2013 09/17/2013 Journal Article