MARC details
000 -LEADER |
fixed length control field |
04515nam a22006017a 4500 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
240723s20242024 xxu||||| |||| 00| 0 eng d |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
International Standard Serial Number |
1078-1439 |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
S1078-1439(24)00009-7 [pii] |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
Ovid MEDLINE(R) |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
PMID |
38418269 |
245 ## - TITLE STATEMENT |
Title |
Functional and oncologic outcomes of prostate capsule-sparing radical cystectomy: A systematic review and meta-analysis. [Review] |
251 ## - Source |
Source |
Urologic Oncology. 42(5):121-132, 2024 May. |
252 ## - Abbreviated Source |
Abbreviated source |
UROL. ONCOL.. 42(5):121-132, 2024 May. |
253 ## - Journal Name |
Journal name |
Urologic oncology |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Year |
2024 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Publication date |
2024 May |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Manufacturer |
FY2024 |
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
Publication status |
ppublish |
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
Medline status |
MEDLINE |
520 ## - SUMMARY, ETC. |
Abstract |
Radical cystectomy (RC) is the gold standard treatment for patients with organ-confined bladder cancer. However, despite the success of this treatment, many men who undergo orthotopic neobladder substitution develop significant erectile dysfunction and urinary symptoms, including daytime and nighttime urinary incontinence. Prostate-capsule-sparing radical cystectomy (PCS-RC) with orthotopic neobladder (ONB) has been described in the literature as a surgical technique to improve functional outcomes in appropriately selected patients. We performed a systematic review and meta-analysis of manuscripts on PCS-RC with ONB published after 2000. We included retrospective and prospective studies with more than 25 patients and compared PCS-RC with nerve-sparing or conventional RC. Studies in which the entire prostate was spared (including the transitional zone) were excluded. Comparative studies were analyzed to assess rates of daytime continence, nighttime continence, and satisfactory erectile function in patients undergoing PCS-RC compared with those undergoing conventional RC. Fourteen reports were included in the final review. Our data identify high rates of daytime (83%-97%) and nighttime continence (60%-80%) in patients undergoing PCS-RC with ONB. In comparative studies, meta-analysis results demonstrate no difference in daytime continence (RR:1.12; 95% CI: 0.72-1.73) in those undergoing PCS-RC compared to those undergoing conventional RC. Similarly, nighttime continence was similar between the 2 groups (RR:1.85; 95% CI: 0.57-6.00. Erectile function was improved in those undergoing PCS-RC (RR 5.35; 95% CI: 1.82-15.74) in the PCS-RC series. Bladder cancer margin positivity and recurrence rates were similar to those reported in the literature with conventional RC with an average weighted follow-up of 52.2 months. While several studies utilized different prostate cancer (CaP) screening techniques, the rates of CaP were low (incidence 0.02; 95% CI:0.01-0.04), and oncologic outcomes were similar to standard RC. PCS-RC is associated with improved nighttime continence and erectile function compared to conventional RC techniques. Further work is needed to standardize CaP screening before surgery, but the data suggest low rates of CaP with similar oncologic outcomes when compared to RC. Copyright © 2024 Elsevier Inc. All rights reserved. |
546 ## - LANGUAGE NOTE |
Language note |
English |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
*Erectile Dysfunction |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
*Urinary Bladder Neoplasms |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Cystectomy/mt [Methods] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Erectile Dysfunction/et [Etiology] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Erectile Dysfunction/su [Surgery] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Humans |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Male |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Prospective Studies |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Prostate/su [Surgery] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Retrospective Studies |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Treatment Outcome |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Urinary Bladder Neoplasms/et [Etiology] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Indexing |
Automated |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Health Research Institute |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Washington Hospital Center |
656 ## - INDEX TERM--OCCUPATION |
Department |
MedStar Georgetown University Hospital/MedStar Washington Hospital Center |
656 ## - INDEX TERM--OCCUPATION |
Department |
Urology |
656 ## - INDEX TERM--OCCUPATION |
Department |
Urology Residency - Categorical |
657 ## - INDEX TERM--FUNCTION |
Medline publication type |
Journal Article |
657 ## - INDEX TERM--FUNCTION |
Medline publication type |
Meta-Analysis |
657 ## - INDEX TERM--FUNCTION |
Medline publication type |
Review |
657 ## - INDEX TERM--FUNCTION |
Medline publication type |
Systematic Review |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Chou, JiLing |
Institution Code |
MHRI |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Dall, Christopher P |
Institution Code |
MWHC |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Goldman, Charlotte |
Institution Code |
MGUH |
Program |
Urology Residency - Categorical |
Degree |
MD |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Krasnow, Ross E |
Institution Code |
MWHC |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Mason, James |
Institution Code |
MGUH |
Program |
Urology Residency - Categorical |
Degree |
MD |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Stamatakis, Lambros |
Institution Code |
MWHC |
790 ## - Authors |
All authors |
Dall CP, Mason JB, Goldman CC, Fabrizio G, Alagha EC, Chou J, Kowalczyk KJ, Agarwal PK, Stamatakis L, Krasnow RE |
856 ## - ELECTRONIC LOCATION AND ACCESS |
DOI |
<a href="https://dx.doi.org/10.1016/j.urolonc.2024.01.008">https://dx.doi.org/10.1016/j.urolonc.2024.01.008</a> |
Public note |
https://dx.doi.org/10.1016/j.urolonc.2024.01.008 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Koha item type |
Journal Article |
Item type description |
Article |