Markedly elevated high-sensitivity troponin and in-hospital mortality after cardiac surgery. (Record no. 14440)

MARC details
000 -LEADER
fixed length control field 03655nam a22005417a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 240807s20242024 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 1878-0938
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code S1553-8389(24)00463-9 [pii]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 38719633
245 ## - TITLE STATEMENT
Title Markedly elevated high-sensitivity troponin and in-hospital mortality after cardiac surgery.
251 ## - Source
Source Cardiovascular Revascularization Medicine. 2024 May 05
252 ## - Abbreviated Source
Abbreviated source Cardiovasc Revasc Med. 2024 May 05
253 ## - Journal Name
Journal name Cardiovascular revascularization medicine : including molecular interventions
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2024
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Manufacturer FY2024
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Publication date 2024 May 05
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status aheadofprint
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Medline status Publisher
266 ## - Date added to catalog
Date added to catalog 2024-08-07
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Date Medline record created 2024/05/08 22:01
501 ## - WITH NOTE
Local holdings Available in print through MWHC library: 2002 - present
520 ## - SUMMARY, ETC.
Abstract BACKGROUND: High-sensitivity troponin (hsTnI) is correlated with cardiac mortality; however, studies on the relationship of markedly elevated hsTnI with in-hospital mortality after cardiac surgery are sparse. Therefore, we aimed to define this relationship in order to help guide in-hospital, acute management of post-surgical patients.
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Abstract CONCLUSION: Increasing hsTnI level is associated with increasing probability of in-hospital mortality and, therefore, serves as an additional, objective measure of risk to help guide in-hospital clinical management. Copyright © 2024 Elsevier Inc. All rights reserved.
520 ## - SUMMARY, ETC.
Abstract METHODS: We retrospectively analyzed all cardiac surgeries completed at our institution between January 2020 and June 2022 in which a peak hsTnI was noted to be >35x upper limit of normal (ULN = 34 ng/L). The primary outcome was in-hospital death. Subgroup analysis was performed to assess differences between coronary artery bypass grafting (CABG) and other cardiac surgeries.
520 ## - SUMMARY, ETC.
Abstract RESULTS: A total of 1382 cases met inclusion criteria. The patients' mean age was 64.8 years and 68.2 % were male. Median peak hsTnI after surgery was 4202 ng/L (interquartile ratio: 2427-7654). Univariate analysis of troponin level with mortality found that for every 1000 ng/L increase in hsTnI, odds of in-hospital death increased by 3.8 % (odds ratio [OR]: 1.038; 95 % confidence interval [CI] 1.027-1.050; p < 0.0001). In a multivariate model, troponin (OR 1.02; 95 % CI 1.01-1.04; p = 0.004) maintained a significant association with in-hospital death. CABG was associated with a lower risk of in-hospital death for any given hsTnI level up to 60,000 ng/L compared to other cardiac surgeries.
546 ## - LANGUAGE NOTE
Language note English
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Topical term or geographic name entry element IN PROCESS -- NOT YET INDEXED
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Indexing Automated
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Heart & Vascular Institute
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Institution MedStar Washington Hospital Center
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Department Advanced Cardiac Catheterization Research Fellowship
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Department Interventional Cardiology Fellowship
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Medline publication type Journal Article
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Local Authors Aladin, Amer
Institution Code MWHC
Program Interventional Cardiology Fellowship
Degree MBChB
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Local Authors Ben-Dor, Itsik
Institution Code MHVI
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Bhogal, Sukhdeep
Institution Code MHVI
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Cellamare, Matteo
Institution Code MHVI
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Local Authors Merdler, Ilan
Institution Code MHVI
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Reddy, Pavan
Institution Code MWHC
Program Advanced Cardiac Catheterization Research Fellowship
Degree MD
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Local Authors Rogers, Toby
Institution Code MHVI
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Satler, Lowell F
Institution Code MHVI
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Waksman, Ron
Institution Code MHVI
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Zhang, Cheng
Institution Code MHVI
790 ## - Authors
All authors Reddy P, Cellamare M, Merdler I, Zhang C, Bhogal S, Aladin AI, Ben-Dor I, Satler LF, Rogers T, Waksman R
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.1016/j.carrev.2024.05.005">https://dx.doi.org/10.1016/j.carrev.2024.05.005</a>
Public note https://dx.doi.org/10.1016/j.carrev.2024.05.005
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Barcode Date last seen Price effective from Koha item type
              08/07/2024   38719633 08/07/2024 08/07/2024 Journal Article

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