The role of focused ultrasound for pediatric brain tumors: current insights and future implications on treatment strategies. (Record no. 14441)

MARC details
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fixed length control field 03142nam a22004337a 4500
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fixed length control field 240807s20242024 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 0256-7040
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.1007/s00381-024-06413-9 [pii]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 38702518
245 ## - TITLE STATEMENT
Title The role of focused ultrasound for pediatric brain tumors: current insights and future implications on treatment strategies.
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Source Childs Nervous System. 2024 May 03
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Abbreviated source Childs Nerv Syst. 2024 May 03
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Journal name Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
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Year 2024
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Manufacturer FY2024
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Publication date 2024 May 03
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status aheadofprint
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Medline status Publisher
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Date added to catalog 2024-08-07
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Date Medline record created 2024/05/03 23:29
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Abstract CONCLUSION: Discussions regarding future applications of FUS for the treatment of gliomas include improved drug delivery, immunomodulation, radiosensitization, and other technological advancements. Copyright © 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
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Abstract INTRODUCTION: Focused ultrasound (FUS) is an innovative and emerging technology for the treatment of adult and pediatric brain tumors and illustrates the intersection of various specialized fields, including neurosurgery, neuro-oncology, radiation oncology, and biomedical engineering.
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Abstract METHODS: The fundamental principles of FUS include its ability to induce thermal ablation or enhance drug delivery through transient blood-brain barrier (BBB) disruption, emphasizing the adaptability of high-intensity focused ultrasound (HIFU) and low-intensity focused ultrasound (LIFU) applications.
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Abstract OBJECTIVE: The authors provide a comprehensive overview of the application and implications of FUS in treating pediatric brain tumors, with a special focus on pediatric low-grade gliomas (pLGGs) and the evolving landscape of this technology and its clinical utility.
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Abstract RESULTS: Several ongoing clinical trials explore the potential of FUS in offering alternative therapeutic strategies for pathologies where conventional treatments fall short, specifically centrally-located benign CNS tumors and diffuse intrinsic pontine glioma (DIPG). A case illustration involving the use of HIFU for pilocytic astrocytoma is presented.
546 ## - LANGUAGE NOTE
Language note English
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Topical term or geographic name entry element IN PROCESS -- NOT YET INDEXED
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Indexing Automated
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Department MedStar Georgetown University Hospital/MedStar Washington Hospital Center
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Department Neurosurgery Residency
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Medline publication type Journal Article
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Local Authors Chesney, Kelsi
Institution Code MGUH
Program Neurosurgery Residency
Degree MD
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Local Authors Keating, Gregory
Institution Code MGUH
Program Neurosurgery Residency
Degree MD
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Local Authors Patel, Nirali
Institution Code MGUH
Program Neurosurgery Residency
Degree MD
790 ## - Authors
All authors Chesney KM, Keating GF, Patel N, Kilburn L, Fonseca A, Wu CC, Nazarian J, Packer RJ, Donoho DA, Oluigbo C, Myseros JS, Keating RF, Syed HR
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DOI <a href="https://dx.doi.org/10.1007/s00381-024-06413-9">https://dx.doi.org/10.1007/s00381-024-06413-9</a>
Public note https://dx.doi.org/10.1007/s00381-024-06413-9
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
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Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Barcode Date last seen Price effective from Koha item type
              08/07/2024   38702518 08/07/2024 08/07/2024 Journal Article

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