MARC details
000 -LEADER |
fixed length control field |
02355nam a22004457a 4500 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
221213s20222022 xxu||||| |||| 00| 0 eng d |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
International Standard Serial Number |
1198-0052 |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.3390/curroncol29100541 [doi] |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
curroncol29100541 [pii] |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
PMC9600738 [pmc] |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
Ovid MEDLINE(R) |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
PMID |
36290818 |
245 ## - TITLE STATEMENT |
Title |
The Role of Immunotherapy in Pancreatic Cancer. [Review] |
251 ## - Source |
Source |
Current Oncology. 29(10):6864-6892, 2022 Sep 23. |
252 ## - Abbreviated Source |
Abbreviated source |
Curr. oncol.. 29(10):6864-6892, 2022 Sep 23. |
253 ## - Journal Name |
Journal name |
Current oncology (Toronto, Ont.) |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Year |
2022 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Manufacturer |
FY2023 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Publication date |
2022 Sep 23 |
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
Publication status |
epublish |
266 ## - Date added to catalog |
Date added to catalog |
2022-12-13 |
501 ## - WITH NOTE |
Local holdings |
Available online through MWHC library: 2006 - present |
520 ## - SUMMARY, ETC. |
Abstract |
Pancreatic adenocarcinoma remains one of the most lethal cancers globally, with a significant need for improved therapeutic options. While the recent breakthroughs of immunotherapy through checkpoint inhibitors have dramatically changed treatment paradigms in other malignancies based on considerable survival benefits, this is not so for pancreatic cancer. Chemotherapies with modest benefits are still the cornerstone of advanced pancreatic cancer treatment. Pancreatic cancers are inherently immune-cold tumors and have been largely refractory to immunotherapies in clinical trials. Understanding and overcoming the current failures of immunotherapy through elucidating resistance mechanisms and developing novel therapeutic approaches are essential to harnessing the potential durable benefits of immune-modulating therapy in pancreatic cancer patients. |
546 ## - LANGUAGE NOTE |
Language note |
English |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
*Adenocarcinoma |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
*Pancreatic Neoplasms |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Humans |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Immunologic Factors |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Immunotherapy |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Pancreatic Neoplasms/dt [Drug Therapy] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Pancreatic Neoplasms/pa [Pathology] |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Washington Hospital Center |
656 ## - INDEX TERM--OCCUPATION |
Department |
Internal Medicine Residency |
657 ## - INDEX TERM--FUNCTION |
Medline publication type |
Journal Article |
657 ## - INDEX TERM--FUNCTION |
Medline publication type |
Review |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Debnath, Dipanjan |
Institution Code |
MWHC |
Program |
Internal Medicine Residency |
Degree |
MBBS |
Resident year |
Resident PGY 3 |
790 ## - Authors |
All authors |
Debnath D, Hartley ML, Mukherji R, Noel MS |
856 ## - ELECTRONIC LOCATION AND ACCESS |
DOI |
<a href="https://dx.doi.org/10.3390/curroncol29100541">https://dx.doi.org/10.3390/curroncol29100541</a> |
Public note |
https://dx.doi.org/10.3390/curroncol29100541 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Koha item type |
Journal Article |
Item type description |
Article |