Nonvascularized Cartilage Grafts Versus Vascularized Cartilage Flaps: Comparison of Cartilage Quality 6 Months After Transfer and Isolated From Surrounding Bone Ingrowth. (Record no. 2815)

MARC details
000 -LEADER
fixed length control field 04213nam a22005297a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 171110s20182018 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 0363-5023
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 29033290
245 ## - TITLE STATEMENT
Title Nonvascularized Cartilage Grafts Versus Vascularized Cartilage Flaps: Comparison of Cartilage Quality 6 Months After Transfer and Isolated From Surrounding Bone Ingrowth.
251 ## - Source
Source Journal of Hand Surgery - American Volume. 43(2):188.e1-188.e8, 2018 02.
252 ## - Abbreviated Source
Abbreviated source J Hand Surg [Am]. 43(2):188.e1-188.e8, 2018 02.
252 ## - Abbreviated Source
Former abbreviated source J Hand Surg [Am]. , 2017 Oct 12
253 ## - Journal Name
Journal name The Journal of hand surgery
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2018
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Manufacturer FY2018
266 ## - Date added to catalog
Date added to catalog 2017-11-10
268 ## - Previous citation
-- Journal of Hand Surgery - American Volume. , 2017 Oct 12
501 ## - WITH NOTE
Local holdings Available in print through MWHC library: 1999 - 2002, Available online from MWHC library: 1995 - present
520 ## - SUMMARY, ETC.
Abstract CLINICAL RELEVANCE: In locations in which perfusion from surrounding bone may be limited (ie, proximal scaphoid or proximal lunate reconstruction), articular reconstruction using vascularized osteochondral flaps will yield superior cartilage organization and architecture than nonvascularized osteochondral grafts. The clinical and functional relevance of this finding requires further study.
520 ## - SUMMARY, ETC.
Abstract CONCLUSIONS: When deprived of subchondral perfusion from underlying bone, osteochondral vascularized flaps in an intrasynovial environment demonstrate superior cartilage quality and survival compared with nonvascularized grafts.
520 ## - SUMMARY, ETC.
Abstract Copyright (c) 2017 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved.
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Abstract METHODS: Two adjacent osteochondral segments were harvested on the medial femoral trochlea in domestic 6- to 8-month-old pigs. Each segment measured approximately 12 mm x 15 mm x 17 mm. One segment was maintained on the descending geniculate artery vascular pedicle. The adjacent segment was separated from the pedicle to serve as a nonvascularized graft. A thin layer of methylmethacrylate cement was used to line the harvest site defect to prevent vascular ingrowth to the subsequently replaced specimens. The pigs were maintained on a high-calorie feed and returned to ambulation and full weight-bearing on the surgical legs. The animals were sacrificed after 6 months and the specimens were reharvested, sectioned, and examined. The cartilage was graded by 2 pathologists blinded to the origin of specimens as vascularized flaps or nonvascularized grafts.
520 ## - SUMMARY, ETC.
Abstract PURPOSE: Subchondral perfusion of osteochondral grafts has been shown to be important in preventing long-term cartilage degeneration. In carpal reconstruction, subchondral perfusion from the graft bed is limited. This study's purpose was to compare the histological characteristics of cartilage in osteochondral grafts supported by synovial imbibition alone to cartilage of vascularized osteochondral flaps that have both synovial and vascular pedicle perfusion.
520 ## - SUMMARY, ETC.
Abstract RESULTS: All specimens were assigned scores utilizing the International Cartilage Repair Society grading system. Scoring for chondrocyte viability, cartilage surface morphology, and cell and matrix appearance was significantly higher in the vascularized osteochondral group than in the graft group.
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Cartilage
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Femur
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Surgical Flaps/bs [Blood Supply]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Animals
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Cartilage/bs [Blood Supply]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Cartilage/tr [Transplantation]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Cell Survival
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Chondrocytes/cy [Cytology]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Femur/bs [Blood Supply]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Femur/tr [Transplantation]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Microscopy
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Models, Animal
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Swine
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Union Memorial Hospital
656 ## - INDEX TERM--OCCUPATION
Department Curtis National Hand Center
657 ## - INDEX TERM--FUNCTION
Medline publication type Journal Article
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Higgins, James P
790 ## - Authors
All authors Benlidayi ME, Borumandi F, Burger HK, Gaggl AJ, Higgins JP, Polat S, Sencar L, Vasilyeva A
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.1016/j.jhsa.2017.09.014">https://dx.doi.org/10.1016/j.jhsa.2017.09.014</a>
Public note https://dx.doi.org/10.1016/j.jhsa.2017.09.014
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
          MedStar Authors Catalog MedStar Authors Catalog 11/10/2017   29033290 29033290 11/10/2017 11/10/2017 Journal Article

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