MARC details
000 -LEADER |
fixed length control field |
02992nam a22003617a 4500 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
200709s20202020 xxu||||| |||| 00| 0 eng d |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
International Standard Serial Number |
2524-8987 |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.1186/s13089-020-00163-w [doi] |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.1186/s13089-020-00163-w [pii] |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
PMC7142196 [pmc] |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
Ovid MEDLINE(R) |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
PMID |
32270297 |
245 ## - TITLE STATEMENT |
Title |
Quantifying systemic congestion with Point-Of-Care ultrasound: development of the venous excess ultrasound grading system. |
251 ## - Source |
Source |
The Ultrasound Journal. 12(1):16, 2020 Apr 09. |
252 ## - Abbreviated Source |
Abbreviated source |
Ultrasound J. 12(1):16, 2020 Apr 09. |
253 ## - Journal Name |
Journal name |
The ultrasound journal |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Year |
2020 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Manufacturer |
FY2020 |
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
Publication status |
epublish |
266 ## - Date added to catalog |
Date added to catalog |
2020-07-09 |
520 ## - SUMMARY, ETC. |
Abstract |
BACKGROUND: Organ congestion is a mediator of adverse outcomes in critically ill patients. Point-Of-Care ultrasound (POCUS) is widely available and could enable clinicians to detect signs of venous congestion at the bedside. The aim of this study was to develop several grading system prototypes using POCUS and to determine their respective ability to predict acute kidney injury (AKI) after cardiac surgery. This is a post-hoc analysis of a single-center prospective study in 145 patients undergoing cardiac surgery for which repeated daily measurements of hepatic, portal, intra-renal vein Doppler and inferior vena cava (IVC) ultrasound were performed during the first 72 h after surgery. Five prototypes of venous excess ultrasound (VExUS) grading system combining multiple ultrasound markers were developed. |
520 ## - SUMMARY, ETC. |
Abstract |
CONCLUSIONS: The combination of multiple POCUS markers may identify clinically significant venous congestion. |
520 ## - SUMMARY, ETC. |
Abstract |
RESULTS: The association between each score and AKI was assessed using time-dependant Cox models as well as conventional performance measures of diagnostic testing. A total of 706 ultrasound assessments were analyzed. We found that defining severe venous congestion as the presence of severe flow abnormalities in multiple Doppler patterns with a dilated IVC (>= 2 cm) showed the strongest association with the development of subsequent AKI compared with other combinations (HR: 3.69 CI 1.65-8.24 p = 0.001). The association remained significant after adjustment for baseline risk of AKI and vasopressor/inotropic support (HR: 2.82 CI 1.21-6.55 p = 0.02). Furthermore, this severe VExUS grade offered a useful positive likelihood ratio (+LR: 6.37 CI 2.19-18.50) when detected at ICU admission, which outperformed central venous pressure measurements. |
546 ## - LANGUAGE NOTE |
Language note |
English |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
IN PROCESS -- NOT YET INDEXED |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Washington Hospital Center |
656 ## - INDEX TERM--OCCUPATION |
Department |
Emergency Medicine |
657 ## - INDEX TERM--FUNCTION |
Medline publication type |
Journal Article |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Spiegel, Rory |
790 ## - Authors |
All authors |
Beaubien-Souligny W, Bouchard J, Denault AY, Haycock K, Lamarche Y, Rola P, Spiegel R |
856 ## - ELECTRONIC LOCATION AND ACCESS |
DOI |
<a href="https://dx.doi.org/10.1186/s13089-020-00163-w">https://dx.doi.org/10.1186/s13089-020-00163-w</a> |
Public note |
https://dx.doi.org/10.1186/s13089-020-00163-w |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Koha item type |
Journal Article |
Item type description |
Article |