Quantifying systemic congestion with Point-Of-Care ultrasound: development of the venous excess ultrasound grading system. (Record no. 5163)

MARC details
000 -LEADER
fixed length control field 02992nam a22003617a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 200709s20202020 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 2524-8987
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.1186/s13089-020-00163-w [doi]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.1186/s13089-020-00163-w [pii]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code PMC7142196 [pmc]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 32270297
245 ## - TITLE STATEMENT
Title Quantifying systemic congestion with Point-Of-Care ultrasound: development of the venous excess ultrasound grading system.
251 ## - Source
Source The Ultrasound Journal. 12(1):16, 2020 Apr 09.
252 ## - Abbreviated Source
Abbreviated source Ultrasound J. 12(1):16, 2020 Apr 09.
253 ## - Journal Name
Journal name The ultrasound journal
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2020
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Manufacturer FY2020
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status epublish
266 ## - Date added to catalog
Date added to catalog 2020-07-09
520 ## - SUMMARY, ETC.
Abstract BACKGROUND: Organ congestion is a mediator of adverse outcomes in critically ill patients. Point-Of-Care ultrasound (POCUS) is widely available and could enable clinicians to detect signs of venous congestion at the bedside. The aim of this study was to develop several grading system prototypes using POCUS and to determine their respective ability to predict acute kidney injury (AKI) after cardiac surgery. This is a post-hoc analysis of a single-center prospective study in 145 patients undergoing cardiac surgery for which repeated daily measurements of hepatic, portal, intra-renal vein Doppler and inferior vena cava (IVC) ultrasound were performed during the first 72 h after surgery. Five prototypes of venous excess ultrasound (VExUS) grading system combining multiple ultrasound markers were developed.
520 ## - SUMMARY, ETC.
Abstract CONCLUSIONS: The combination of multiple POCUS markers may identify clinically significant venous congestion.
520 ## - SUMMARY, ETC.
Abstract RESULTS: The association between each score and AKI was assessed using time-dependant Cox models as well as conventional performance measures of diagnostic testing. A total of 706 ultrasound assessments were analyzed. We found that defining severe venous congestion as the presence of severe flow abnormalities in multiple Doppler patterns with a dilated IVC (>= 2 cm) showed the strongest association with the development of subsequent AKI compared with other combinations (HR: 3.69 CI 1.65-8.24 p = 0.001). The association remained significant after adjustment for baseline risk of AKI and vasopressor/inotropic support (HR: 2.82 CI 1.21-6.55 p = 0.02). Furthermore, this severe VExUS grade offered a useful positive likelihood ratio (+LR: 6.37 CI 2.19-18.50) when detected at ICU admission, which outperformed central venous pressure measurements.
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element IN PROCESS -- NOT YET INDEXED
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Washington Hospital Center
656 ## - INDEX TERM--OCCUPATION
Department Emergency Medicine
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Medline publication type Journal Article
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Local Authors Spiegel, Rory
790 ## - Authors
All authors Beaubien-Souligny W, Bouchard J, Denault AY, Haycock K, Lamarche Y, Rola P, Spiegel R
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.1186/s13089-020-00163-w">https://dx.doi.org/10.1186/s13089-020-00163-w</a>
Public note https://dx.doi.org/10.1186/s13089-020-00163-w
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
              07/09/2020   32270297 32270297 07/09/2020 07/09/2020 Journal Article

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