MARC details
000 -LEADER |
fixed length control field |
03234nam a22004337a 4500 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
220511s20222022 xxu||||| |||| 00| 0 eng d |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
International Standard Serial Number |
1091-255X |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.1007/s11605-022-05315-y [doi] |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.1007/s11605-022-05315-y [pii] |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
Ovid MEDLINE(R) |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
PMID |
35414141 |
245 ## - TITLE STATEMENT |
Title |
Can Clinical Response Predict Pathologic Response Following Neoadjuvant Chemoradiation for Esophageal Cancer?. |
251 ## - Source |
Source |
Journal of Gastrointestinal Surgery. 2022 Apr 12 |
252 ## - Abbreviated Source |
Abbreviated source |
J Gastrointest Surg. 2022 Apr 12 |
253 ## - Journal Name |
Journal name |
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Year |
2022 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Manufacturer |
FY2022 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Publication date |
2022 Apr 12 |
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
Publication status |
aheadofprint |
266 ## - Date added to catalog |
Date added to catalog |
2022-05-11 |
520 ## - SUMMARY, ETC. |
Abstract |
CONCLUSIONS: Current restaging tools cannot reliably predict ypCR after nCRT. While multimodal restaging appears to be a more accurate predictor of ypCR than any testing modality alone, patients cannot reliably be advised to avoid an esophagectomy on the assumption that ycCR predicts ypCR at this time. Copyright © 2022. The Society for Surgery of the Alimentary Tract. |
520 ## - SUMMARY, ETC. |
Abstract |
METHODS: Patients undergoing esophagectomy following nCRT at three major institutions between 2005 and 2018 were reviewed. Restaging, including PET/CT, endoscopy with biopsy, and esophageal ultrasound (EUS), was performed to determine ycCR. |
520 ## - SUMMARY, ETC. |
Abstract |
OBJECTIVES: Approximately 20-40% of patients with locally advanced esophageal cancer will achieve a pathologic complete response (ypCR) following neoadjuvant chemoradiotherapy (nCRT). Predicting ypCR based on a clinical complete response (ycCR) has been a challenge. This study assessed the correlation between ycCR and ypCR, as determined from esophagectomy specimens. |
520 ## - SUMMARY, ETC. |
Abstract |
RESULTS: Six hundred sixty patients were included, with 93.3% with esophageal adenocarcinoma histology. Six hundred fifty-eight of these patients underwent PET, 304 EUS, and 584 underwent a biopsy. Following nCRT, 148 (22.4%) were found to have a ypCR. Only 12/32 (37.5%) determined to have a ycCR were found to have a ypCR, while 136/628 (21.6%) with a non-ycCR were found to have a ypCR (p 0.075). Individual modality PPV was 28% for PET, 54% for EUS, and 26% for biopsy. When PET was combined with EUS, 168 reports were concordant and the PPV of ypCR was 50%, though the number of patients was low (1/2). With all 3 re-staging modalities combined, the PPV and NPV both rose to 100%. |
546 ## - LANGUAGE NOTE |
Language note |
English |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
IN PROCESS -- NOT YET INDEXED |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Health Research Institute |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Washington Hospital Center |
656 ## - INDEX TERM--OCCUPATION |
Department |
MedStar General Surgery Residency |
656 ## - INDEX TERM--OCCUPATION |
Department |
MedStar Georgetown University Hospital/MedStar Washington Hospital Center |
656 ## - INDEX TERM--OCCUPATION |
Department |
Surgery/Thoracic Surgery |
657 ## - INDEX TERM--FUNCTION |
Medline publication type |
Journal Article |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Desale, Sameer |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Holliday, Tyler |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Khaitan, Puja G |
790 ## - Authors |
All authors |
Bayley EM, Carroll A, Desale S, Hofstetter WL, Holliday T, Khaitan PG, Watson TJ, Zhou N |
856 ## - ELECTRONIC LOCATION AND ACCESS |
DOI |
<a href="https://dx.doi.org/10.1007/s11605-022-05315-y">https://dx.doi.org/10.1007/s11605-022-05315-y</a> |
Public note |
https://dx.doi.org/10.1007/s11605-022-05315-y |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Koha item type |
Journal Article |
Item type description |
Article |