Hemodynamics and Subclinical Leaflet Thrombosis in Low-Risk Patients Undergoing Transcatheter Aortic Valve Replacement. (Record no. 8342)

000 -LEADER
fixed length control field 05332nam a22011657a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 200103s20192019 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 1941-9651
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.1161/CIRCIMAGING.119.009608 [doi]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
Classification number 31826675
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Asch, Federico M
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Ben-Dor, Itsik
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Craig, Paige E
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Garcia-Garcia, Hector M
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Khan, Jaffar M
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Kolm, Paul
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Medvedofsky, Diego
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Rogers, Toby
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Satler, Lowell F
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Shults, Christian
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Torguson, Rebecca
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Waksman, Ron
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Weissman, Gaby
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Zhang, Cheng
190 ## -
-- Asch FM
190 ## -
-- Ben-Dor I
190 ## -
-- Bilfinger T
190 ## -
-- Buchanan S
190 ## -
-- Buchbinder M
190 ## -
-- Butzel D
190 ## -
-- Craig PE
190 ## -
-- Ehsan A
190 ## -
-- Garcia-Garcia HM
190 ## -
-- Garrett R
190 ## -
-- Goncalves J
190 ## -
-- Gordon P
190 ## -
-- Hahn C
190 ## -
-- Hanna N
190 ## -
-- Khan JM
190 ## -
-- Kolm P
190 ## -
-- Levitt R
190 ## -
-- Medvedofsky D
190 ## -
-- Parikh P
190 ## -
-- Rogers T
190 ## -
-- Satler LF
190 ## -
-- Shults C
190 ## -
-- Torguson R
190 ## -
-- Waksman R
190 ## -
-- Weissman G
190 ## -
-- Wilson SR
190 ## -
-- Zhang C
245 ## - TITLE STATEMENT
Title Hemodynamics and Subclinical Leaflet Thrombosis in Low-Risk Patients Undergoing Transcatheter Aortic Valve Replacement.
251 ## -
-- Circulation. Cardiovascular imaging. 12(12):e009608, 2019 Dec.
251 ## -
-- Circulation. Cardiovascular imaging. 12(12):e009608, 2019 12.
252 ## -
-- Circ Cardiovasc Imaging. 12(12):e009608, 2019 Dec.
252 ## -
-- Circ Cardiovasc Imaging. 12(12):e009608, 2019 12.
253 ## -
-- Circulation. Cardiovascular imaging
260 ## - PUBLICATION, DISTRIBUTION, ETC.
-- 2019
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Date of publication, distribution, etc. 2019
260 ## - PUBLICATION, DISTRIBUTION, ETC.
-- ppublish
269 ## -
-- FY2020
520 ## - SUMMARY, ETC.
Summary, etc. BACKGROUND: This analysis evaluated echocardiographic predictors of hypoattenuated leaflet thickening (HALT) in low-risk patients undergoing transcatheter aortic valve replacement and assessed 1-year clinical and hemodynamic consequences. HALT by computed tomography may be associated with early valve degeneration and increased neurological events.
520 ## - SUMMARY, ETC.
Summary, etc. CLINICAL TRIAL REGISTRATION: URL: http://www.clinicaltrials.gov. Unique identifier: NCT02628899.
520 ## - SUMMARY, ETC.
Summary, etc. CONCLUSIONS: There were no early hemodynamic predictors of HALT. At 30 days, patients with HALT had worse valve hemodynamics than those without HALT, but hemodynamic and clinical outcomes at 1 year were similar.
520 ## - SUMMARY, ETC.
Summary, etc. METHODS: Echocardiograms were performed at baseline, discharge, 30 days, and 1 year post-procedure. Four-dimensional contrast-enhanced computed tomography assessed HALT at 30 days. Independent core laboratories analyzed images. Doppler hemodynamic parameters were tested in a univariable regression model to identify HALT predictors. One-year clinical and hemodynamic outcomes were compared between HALT (+) and (-) patients.
520 ## - SUMMARY, ETC.
Summary, etc. RESULTS: Analysis included 170 patients with Sapien 3 valves and diagnostic 30-day computed tomographies, of whom 27 (16%) had HALT. Baseline characteristics were similar between groups. After transcatheter aortic valve replacement, aortic flow was nonsignificantly reduced in patients who developed HALT. Regression analysis did not show significant association between baseline or discharge valve hemodynamics and development of HALT at 30 days. Patients with HALT had smaller aortic valve areas (1.4+/-0.4 versus 1.7+/-0.5 cm2; P=0.018) and Doppler velocity index (0.4+/-0.1 versus 0.5+/-0.1; P=0.003) than those without HALT at 30 days but not at 1 year. There was no difference in aortic mean gradient at 30 days. There was no difference between the groups in New York Heart Association class, 6-minute walk distance, and mortality at 1 year.
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Aged
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element United States
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Treatment Outcome
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Transcatheter Aortic Valve Replacement/is [Instrumentation]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Transcatheter Aortic Valve Replacement/ae [Adverse Effects]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Time Factors
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Thrombosis/pp [Physiopathology]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Thrombosis/et [Etiology]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Thrombosis/dg [Diagnostic Imaging]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Risk Factors
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Risk Assessment
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Prosthesis Failure
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Prospective Studies
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Predictive Value of Tests
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Male
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Humans
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Hemodynamics
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Heart Valve Prosthesis
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Four-Dimensional Computed Tomography
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Female
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Echocardiography, Doppler
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Aortic Valve Stenosis/su [Surgery]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Aortic Valve Stenosis/pp [Physiopathology]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Aortic Valve Stenosis/dg [Diagnostic Imaging]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Aortic Valve/su [Surgery]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Aortic Valve/pp [Physiopathology]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Aortic Valve/dg [Diagnostic Imaging]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Aged, 80 and over
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Geographic name MedStar Heart & Vascular Institute
657 ## - INDEX TERM--FUNCTION
Function Journal Article
857 ## -
-- https://dx.doi.org/10.1161/CIRCIMAGING.119.009608
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection code Permanent Location Current Location Date acquired Barcode Date last seen Price effective from Koha item type
          MedStar Authors Catalog MedStar Authors Catalog 2020-01-03 31826675 2020-01-03 2020-01-03 Journal Article

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