The Impact of Clostridium Difficile Infections on In-Hospital Outcomes of Venous Thromboembolism (Deep Vein Thrombosis or Pulmonary Embolism) Hospitalizations. (Record no. 8991)

000 -LEADER
fixed length control field 03016nam a22003737a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 200902s20202020 xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
Classification number 32685328
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 2168-8184
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.7759/cureus.9195 [doi]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code PMC7366047 [pmc]
190 ## -
-- Jhaveri K
190 ## -
-- Som A
190 ## -
-- Padala SA
190 ## -
-- Surani S
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Jhaveri, Khushali
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Som, Aniruddh
245 ## - TITLE STATEMENT
Title The Impact of Clostridium Difficile Infections on In-Hospital Outcomes of Venous Thromboembolism (Deep Vein Thrombosis or Pulmonary Embolism) Hospitalizations.
251 ## -
-- Cureus. 12(7):e9195, 2020 Jul 15.
252 ## -
-- Cureus. 12(7):e9195, 2020 Jul 15.
253 ## -
-- Cureus
260 ## - PUBLICATION, DISTRIBUTION, ETC.
-- epublish
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Date of publication, distribution, etc. 2020
269 ## -
-- FY2021
520 ## - SUMMARY, ETC.
Summary, etc. Background Clostridium difficile infection (CDI) is associated with high mortality. Studies have shown an increased rate of venous thromboembolism (VTE) in patients with CDI. However, literature regarding the impact of CDI on outcomes of VTE-related hospitalizations is scarce. Our study aimed to assess the impact of CDI on in-hospital outcomes among VTE hospitalizations. Methods The 2016 National Inpatient Sample (NIS) was used to identify all adult hospitalizations in the United States with a primary discharge diagnosis of acute VTE. Hospitalizations with deep vein thrombosis (DVT) or pulmonary embolism (PE) were included under VTE. The sample was stratified based on the presence or absence of active CDI. Chi-square test and weighted Student's t-test were used to analyze categorical and continuous variables, respectively. The adjusted odds ratio (OR) for clinical outcomes were calculated using multivariate logistic regression analysis. Subgroup analyses for DVT and PE hospitalizations were performed. All analyses were completed in SAS (SAS Institute Inc., Cary, NC), and a p-value of <0.05 was considered statistically significant. Results We identified 382,585 weighted hospitalizations for VTE. Among them, 0.8% had concomitant CDI. The presence of CDI was associated with a statistically significant increase in in-hospital mortality (6% vs. 3%), hospitalization cost (
-- 47,356.5 vs.
-- 5,193), and length of stay (13.7 vs. 5.4 days). There were more incidents of bleeding and acute respiratory failure requiring prolonged ventilation in patients with CDI. The odds of stroke were significantly higher in patients with CDI and DVT. Conclusion CDI independently increased in-hospital mortality in VTE. Preventing CDI in the VTE population may mitigate complications, improve in-hospital outcomes, and reduce treatment costs. Copyright (c) 2020, Jhaveri et al.
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element IN PROCESS -- NOT YET INDEXED
656 ## - INDEX TERM--OCCUPATION
Occupation Medicine/Internal Medicine
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Geographic name MedStar Washington Hospital Center
657 ## - INDEX TERM--FUNCTION
Function Journal Article
857 ## -
-- https://dx.doi.org/10.7759/cureus.9195
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier https://dx.doi.org/10.7759/cureus.9195
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection code Permanent Location Current Location Date acquired Barcode Date last seen Price effective from Koha item type
          MedStar Authors Catalog MedStar Authors Catalog 2020-09-02 32685328 2020-09-02 2020-09-02 Journal Article

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