Sequential MRI in pontine and extrapontine myelinolysis following rapid correction of hyponatremia.

MedStar author(s):
Citation: BMC Research Notes. 11(1):707, 2018 Oct 05.PMID: 30290836Institution: MedStar Washington Hospital CenterDepartment: Neurology | RadiologyForm of publication: Journal ArticleMedline article type(s): Journal ArticleSubject headings: *Dog Diseases/dg [Diagnostic Imaging] | *Hyponatremia/co [Complications] | *Magnetic Resonance Imaging/mt [Methods] | *Myelinolysis, Central Pontine/dg [Diagnostic Imaging] | Animals | Dog Diseases/et [Etiology] | Dog Diseases/pa [Pathology] | Dogs | Myelinolysis, Central Pontine/et [Etiology] | Myelinolysis, Central Pontine/pa [Pathology]Year: 2018ISSN:
  • 1756-0500
Name of journal: BMC research notesAbstract: OBJECTIVE: This study describes the MRI changes associated with pontine and extrapontine myelinolysis secondary to rapid correction of hyponatremia in dogs. The authors discuss the relevance of the results for theories of pathogenesis and for diagnosis of patients.RESULTS: MRI changes associated with pontine and extrapontine myelinolysis first occur on diffusion-weighted imaging. As a generalization, gadolinium enhancement, flair image change and T<sub>2</sub> weighted image abnormality appear sequentially.All authors: Lamotte G, Laureno R, Mark ASFiscal year: FY2019Digital Object Identifier: ORCID: Date added to catalog: 2018-10-10
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Journal Article MedStar Authors Catalog Article 30290836 Available 30290836

OBJECTIVE: This study describes the MRI changes associated with pontine and extrapontine myelinolysis secondary to rapid correction of hyponatremia in dogs. The authors discuss the relevance of the results for theories of pathogenesis and for diagnosis of patients.

RESULTS: MRI changes associated with pontine and extrapontine myelinolysis first occur on diffusion-weighted imaging. As a generalization, gadolinium enhancement, flair image change and T<sub>2</sub> weighted image abnormality appear sequentially.

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