The Effect of Maternal Obesity on Oxytocin Requirements to Achieve Vaginal Delivery.

MedStar author(s):
Citation: American Journal of Perinatology. 37(4):349-356, 2020 03.PMID: 31430825Institution: MedStar Washington Hospital CenterDepartment: Obstetrics and Gynecology/Maternal-Fetal MedicineForm of publication: Journal ArticleMedline article type(s): Journal ArticleSubject headings: *Labor, Induced | *Obesity, Maternal | *Oxytocics/ad [Administration & Dosage] | *Oxytocin/ad [Administration & Dosage] | Adolescent | Adult | Body Mass Index | Delivery, Obstetric | Dose-Response Relationship, Drug | Female | Humans | Middle Aged | Overweight | Pregnancy | Retrospective Studies | Young AdultYear: 2020ISSN:
  • 0735-1631
Name of journal: American journal of perinatologyAbstract: CONCLUSION: Obese women are more likely to require oxytocin rates more than 20 mU/min, higher doses of oxytocin, and greater duration of oxytocin exposure to achieve a vaginal delivery.Copyright Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.OBJECTIVE: Our objective was to determine if obese women are more likely to require oxytocin rates > 20 mU/min to achieve vaginal delivery, compared with normal weight women.RESULTS: There were 4,284 births included in the analysis. Thirty-three per cent of deliveries were among women classified as overweight (body mass index [BMI] 25-29.9 kg/m<sup>2</sup>) and 58% were among women classified as obese (BMI >30.0 kg/m<sup>2</sup>), 12% were classified as class III obesity (BMI >40 kg/m<sup>2</sup>). Overall 110 (2.6%) women required an oxytocin rate of >20 mU/min. Doses of oxytocin >20 mU/min for women in the overweight, class I obesity, and class II obesity groups were 2.6, 1.9, and 1.6%, respectively. Deliveries among women with class III obesity had a significantly longer duration of oxytocin exposure (10.7 hours) compared with the normal weight group (8.2 hours, p < 0.001), and had a higher maximum rate of oxytocin compared (10 mU/min) to normal weight women (8 mU/min, p < 0.001).STUDY DESIGN: This is a retrospective cohort study of deliveries at the MedStar Washington Hospital Center and MedStar Georgetown University Hospital.All authors: Adams AD, Coviello EM, Drassinower DOriginally published: American Journal of Perinatology. 2019 Aug 20Fiscal year: FY2020Digital Object Identifier: ORCID: Date added to catalog: 2019-08-27
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Journal Article MedStar Authors Catalog Article 31430825 Available 31430825

CONCLUSION: Obese women are more likely to require oxytocin rates more than 20 mU/min, higher doses of oxytocin, and greater duration of oxytocin exposure to achieve a vaginal delivery.

Copyright Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

OBJECTIVE: Our objective was to determine if obese women are more likely to require oxytocin rates > 20 mU/min to achieve vaginal delivery, compared with normal weight women.

RESULTS: There were 4,284 births included in the analysis. Thirty-three per cent of deliveries were among women classified as overweight (body mass index [BMI] 25-29.9 kg/m<sup>2</sup>) and 58% were among women classified as obese (BMI >30.0 kg/m<sup>2</sup>), 12% were classified as class III obesity (BMI >40 kg/m<sup>2</sup>). Overall 110 (2.6%) women required an oxytocin rate of >20 mU/min. Doses of oxytocin >20 mU/min for women in the overweight, class I obesity, and class II obesity groups were 2.6, 1.9, and 1.6%, respectively. Deliveries among women with class III obesity had a significantly longer duration of oxytocin exposure (10.7 hours) compared with the normal weight group (8.2 hours, p < 0.001), and had a higher maximum rate of oxytocin compared (10 mU/min) to normal weight women (8 mU/min, p < 0.001).

STUDY DESIGN: This is a retrospective cohort study of deliveries at the MedStar Washington Hospital Center and MedStar Georgetown University Hospital.

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