Topical sirolimus for treatment of a venolymphatic malformation in an adolescent girl.
Citation: Pediatric Dermatology. 35(6):e406-e407, 2018 Nov.PMID: 30152558Institution: MedStar Washington Hospital CenterDepartment: DermatologyForm of publication: Journal ArticleMedline article type(s): Journal ArticleSubject headings: *Immunosuppressive Agents/ad [Administration & Dosage] | *Sirolimus/ad [Administration & Dosage] | *Vascular Malformations/dt [Drug Therapy] | Administration, Topical | Adolescent | Female | Humans | Treatment OutcomeYear: 2018ISSN:- 0736-8046
- Cardis, Michael A:
- http://orcid.org/0000-0003-4547-101X
Item type | Current library | Collection | Call number | Status | Date due | Barcode |
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Journal Article | MedStar Authors Catalog | Article | 30152558 | Available | 30152558 |
Copyright (c) 2018 Wiley Periodicals, Inc.
Sirolimus has emerged as a promising treatment for complex congenital vascular malformations but is limited because of systemic side effects. Topically compounded formulations, which have been found to be successful in the treatment of several other conditions, are a preferred drug delivery system to provide local therapy. We report a case of a venolymphatic malformation in an adolescent girl treated with topical 1% sirolimus cream leading to improvement in appearance and associated symptoms.
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