Unusual findings on cystoscopy in a patient with detrusor overactivity.

MedStar author(s):
Citation: Female Pelvic Medicine & Reconstructive Surgery. 18(3):186-7, 2012 May-Jun.PMID: 22543775Institution: MedStar Washington Hospital CenterDepartment: Obstetrics and Gynecology/Female Pelvic Medicine and Reconstructive SurgeryForm of publication: Journal ArticleMedline article type(s): Case Reports | Journal ArticleSubject headings: *Cystoscopy | *Lithium Compounds/pk [Pharmacokinetics] | *Urinary Bladder, Overactive/et [Etiology] | *Urothelium/ch [Chemistry] | Aged | Bipolar Disorder/dt [Drug Therapy] | Female | Humans | Lithium Compounds/tu [Therapeutic Use] | Urethra/ch [Chemistry] | Urinary Bladder/ch [Chemistry]ISSN:
  • 2151-8378
Name of journal: Female pelvic medicine & reconstructive surgeryAbstract: BACKGROUND: Chronic lithium ingestion has been shown to cause polyuria and polydipsia in 20% to 40% of patients, secondary to diabetes insipidus. However, it has not been reported to cause lithium deposition in the bladder.CASE: A 77-year-old woman presented to our clinic with complaints of urinary incontinence, urinary urgency, and nocturnal enuresis for the past 3 to 4 years. She denied polydipsia. Her medical history was significant for bipolar disorder for which she had been on lithium therapy for more than 10 years. Metallic deposition was noted in the suburothelium of a urethral biopsy by gross inspection.CONCLUSION: Suburothelial deposition of metal may act as a bladder irritant and account for this patient's overactive bladder symptoms.All authors: Nosti PA, Sokol AIDigital Object Identifier: Date added to catalog: 2013-09-17
Holdings
Item type Current library Collection Call number Status Date due Barcode
Journal Article MedStar Authors Catalog Article Available 22543775

BACKGROUND: Chronic lithium ingestion has been shown to cause polyuria and polydipsia in 20% to 40% of patients, secondary to diabetes insipidus. However, it has not been reported to cause lithium deposition in the bladder.

CASE: A 77-year-old woman presented to our clinic with complaints of urinary incontinence, urinary urgency, and nocturnal enuresis for the past 3 to 4 years. She denied polydipsia. Her medical history was significant for bipolar disorder for which she had been on lithium therapy for more than 10 years. Metallic deposition was noted in the suburothelium of a urethral biopsy by gross inspection.

CONCLUSION: Suburothelial deposition of metal may act as a bladder irritant and account for this patient's overactive bladder symptoms.

English

Powered by Koha