The effect of pelvic organ prolapse severity on improvement in overactive bladder symptoms after pelvic reconstructive surgery.
Citation: International Urogynecology Journal. 24(8):1303-8, 2013 Aug.PMID: 23229418Institution: MedStar Washington Hospital CenterDepartment: Obstetrics and GynecologyForm of publication: Journal ArticleMedline article type(s): Journal ArticleSubject headings: *Gynecologic Surgical Procedures/mt [Methods] | *Pelvic Floor/su [Surgery] | *Pelvic Organ Prolapse/ep [Epidemiology] | *Pelvic Organ Prolapse/su [Surgery] | *Severity of Illness Index | *Urinary Bladder, Overactive/ep [Epidemiology] | *Urinary Bladder, Overactive/su [Surgery] | Aged | Aged, 80 and over | Cohort Studies | Comorbidity | Female | Humans | Logistic Models | Middle Aged | Prevalence | Quality of Life | Reconstructive Surgical Procedures/mt [Methods] | Retrospective Studies | Treatment Outcome | Urinary Incontinence, Urge/ep [Epidemiology] | Urinary Incontinence, Urge/pc [Prevention & Control]Local holdings: Available online through MWHC library: 2010 - presentISSN:- 0937-3462
Item type | Current library | Collection | Call number | Status | Date due | Barcode |
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Journal Article | MedStar Authors Catalog | Article | Available | 23229418 |
Available online through MWHC library: 2010 - present
CONCLUSIONS: Women with coexisting POP and OAB who undergo surgical correction of POP experience improvement in OAB symptoms after surgery, although women with more severe POP may be at a higher risk of persistent frequency or urge incontinence.
INTRODUCTION AND HYPOTHESIS: This study evaluates the effect of baseline pelvic organ prolapse (POP) severity on improvement in overactive bladder (OAB) symptoms after pelvic reconstructive surgery.
METHODS: We performed a retrospective cohort study of women with POP and OAB who underwent surgical correction of symptomatic apical and/or anterior POP. OAB was defined as an affirmative response to item #15 (urinary frequency) and/or item #16 (urge incontinence) of the Pelvic Floor Distress Inventory (PFDI). POP severity was dichotomized as Pelvic Organ Prolapse Quantification (POP-Q) stage 1-2 versus stage 3-4. Our primary outcome was complete resolution or improvement of urinary frequency or urge incontinence on the PFDI 12 months postoperatively.
RESULTS: At 12 months postoperative, 41 (89%) women with stage 1-2 POP versus 47 (85 %) with stage 3-4 POP reported improvement in urinary frequency (p=0.58). Thirty five (90 %) with stage 1-2 and 34 (85 %) with stage 3-4 POP reported improvement in urge incontinence (p=0.74). On multiple logistic regression, women with stage 3-4 POP had a decreased odds of improvement in frequency or urge incontinence compared with women with stage 1-2 POP (adjusted odds ration [AOR]=0.06 [95 % CI 0.01-0.67]), after adjusting for confounders.
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