Infections in intestinal and multivisceral transplant recipients. [Review]

MedStar author(s):
Citation: Infectious Disease Clinics of North America. 27(2):359-77, 2013 Jun.PMID: 23714345Institution: MedStar Washington Hospital CenterDepartment: Surgery/TransplantationForm of publication: Journal ArticleMedline article type(s): Journal Article | ReviewSubject headings: *Gastrointestinal Diseases/su [Surgery] | *Immunocompromised Host | *Opportunistic Infections/ep [Epidemiology] | *Organ Transplantation | *Transplantation | Candidiasis/di [Diagnosis] | Candidiasis/dt [Drug Therapy] | Candidiasis/ep [Epidemiology] | Humans | Opportunistic Infections/di [Diagnosis] | Opportunistic Infections/dt [Drug Therapy] | Postoperative Complications | Preoperative Period | Virus Diseases/di [Diagnosis] | Virus Diseases/dt [Drug Therapy] | Virus Diseases/ep [Epidemiology]Local holdings: Available online from MWHC library: March 1996 - presentISSN:
  • 0891-5520
Name of journal: Infectious disease clinics of North AmericaAbstract: Intestinal and multivisceral transplantation has become an effective treatment option for patients with intestinal failure. More potent immunosuppressive therapy has resulted in a decreased incidence of acute rejection and has improved patient survival. However, infectious complications can cause significant morbidity both before and after transplantation. In comparison with other solid organ transplant recipients, these patients experience higher rates of acute allograft rejection, thus requiring higher levels of immunosuppression and escalating the risk of infection. This article reviews the most common infectious disease complications encountered, and proposes a potential temporal association for types of infections in this patient population. Copyright 2013 Elsevier Inc. All rights reserved.All authors: Fishbein TM, Girlanda R, Rudolph L, Timpone JG JrDigital Object Identifier: Date added to catalog: 2014-02-24
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Journal Article MedStar Authors Catalog Article Available 23714345

Available online from MWHC library: March 1996 - present

Intestinal and multivisceral transplantation has become an effective treatment option for patients with intestinal failure. More potent immunosuppressive therapy has resulted in a decreased incidence of acute rejection and has improved patient survival. However, infectious complications can cause significant morbidity both before and after transplantation. In comparison with other solid organ transplant recipients, these patients experience higher rates of acute allograft rejection, thus requiring higher levels of immunosuppression and escalating the risk of infection. This article reviews the most common infectious disease complications encountered, and proposes a potential temporal association for types of infections in this patient population. Copyright 2013 Elsevier Inc. All rights reserved.

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