COVID-19-Associated Coagulopathy: Ascending Aortic Thrombus.

MedStar author(s):
Citation: Cureus. 15(3):e36607, 2023 Mar.PMID: 37155447Institution: MedStar Union Memorial HospitalDepartment: Hospitalist | Internal Medicine ResidencyForm of publication: Journal ArticleMedline article type(s): Case ReportsSubject headings: Year: 2023ISSN:
  • 2168-8184
Name of journal: CureusAbstract: The mechanism of arterial thrombosis in coronavirus disease 2019 (COVID-19) is not completely understood and is attributed to the complex interactions of endothelial injury, platelet hyperactivation, and activated pro-inflammatory cytokines. Management strategies may include a combination of surgery and anticoagulation, or anticoagulation alone. A 56-year-old woman with recent COVID-19 infection presented with chest pain and dyspnea. Chest CT angiography (CTA) and aortic magnetic resonance imaging revealed an intraluminal thrombus in the mid ascending aorta. A multidisciplinary team decided on heparin infusion. She was transitioned to apixaban and a three-month interval outpatient CTA revealed complete resolution of the aortic thrombus. Copyright © 2023, Mesalles et al.All authors: Mesalles ME, Rao SJ, Sagheer UFiscal year: FY2023Digital Object Identifier: Date added to catalog: 2023-06-26
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Journal Article MedStar Authors Catalog Article 37155447 Available 37155447

The mechanism of arterial thrombosis in coronavirus disease 2019 (COVID-19) is not completely understood and is attributed to the complex interactions of endothelial injury, platelet hyperactivation, and activated pro-inflammatory cytokines. Management strategies may include a combination of surgery and anticoagulation, or anticoagulation alone. A 56-year-old woman with recent COVID-19 infection presented with chest pain and dyspnea. Chest CT angiography (CTA) and aortic magnetic resonance imaging revealed an intraluminal thrombus in the mid ascending aorta. A multidisciplinary team decided on heparin infusion. She was transitioned to apixaban and a three-month interval outpatient CTA revealed complete resolution of the aortic thrombus. Copyright © 2023, Mesalles et al.

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