Characteristics and management of patients with acute coronary syndrome and normal or non-significant coronary artery disease: results from Acute Coronary Syndrome Israeli Survey (ACSIS) 2004-2010.

MedStar author(s):
Citation: Journal of Invasive Cardiology. 26(8):389-93, 2014 Aug.PMID: 25091099Institution: MedStar Heart & Vascular InstituteForm of publication: Journal ArticleMedline article type(s): Journal ArticleSubject headings: *Acute Coronary Syndrome | *Coronary Artery Disease/pp [Physiopathology] | *Disease Management | Acute Coronary Syndrome/di [Diagnosis] | Acute Coronary Syndrome/et [Etiology] | Acute Coronary Syndrome/mo [Mortality] | Acute Coronary Syndrome/pp [Physiopathology] | Acute Coronary Syndrome/th [Therapy] | Age Factors | Aged | Coronary Angiography/mt [Methods] | Coronary Artery Disease/co [Complications] | Coronary Artery Disease/di [Diagnosis] | Female | Health Surveys | Hospital Mortality | Hospitalization/sn [Statistics & Numerical Data] | Humans | Israel/ep [Epidemiology] | Male | Middle Aged | Risk Factors | Sex FactorsYear: 2014Local holdings: Available online from MWHC library: 2001 - present, Available in print through MWHC library: 2003 - 2008ISSN:
  • 1042-3931
Name of journal: The Journal of invasive cardiologyAbstract: BACKGROUND: An important subset of patients presenting with acute coronary syndrome (ACS) are found to have either normal coronaries (NCs) or non-obstructive coronary artery disease (NOCAD; lumen diameter narrowing <50%).CONCLUSIONS: In a real-world practice of ACS, underutilization of evidence-based medications in patients with NC or NOCAD was observed. Nonetheless, its prognostic significance is still unknown and must be explored in larger patient cohorts.METHODS: The Acute Coronary Syndrome Israeli Survey (ACSIS) database was utilized to compare the characteristics and therapeutic approach for patients who underwent angiography for ACS and had either NC (n = 84; 2%), NOCAD (n = 79; 2%), or obstructive coronary artery disease (OCAD; n = 3523; 96%).OBJECTIVES: To explore the characteristics and management strategies in this population in a real-world setting.RESULTS: Baseline characteristics were comparable, save for a younger age and a higher proportion of females in the NC group (P<.001 for both). Prior to admission, chronic anticoagulant therapy was more frequently used in the NC vs. the OCAD group (4.8% vs. 1.6%, respectively; P=.02). Recommended ACS evidence-based medications, both in-hospital and at discharge, were less frequently prescribed to patients with NC or NOCAD.All authors: Blatt A, Gavrielov-Yusim N, Goldenberg I, Gottlieb S, Krakover R, Magalhaes MA, Minha S, Vered ZFiscal year: FY2015Date added to catalog: 2016-09-07
Holdings
Item type Current library Collection Call number Status Date due Barcode
Journal Article MedStar Authors Catalog Article 25091099 Available 25091099

Available online from MWHC library: 2001 - present, Available in print through MWHC library: 2003 - 2008

BACKGROUND: An important subset of patients presenting with acute coronary syndrome (ACS) are found to have either normal coronaries (NCs) or non-obstructive coronary artery disease (NOCAD; lumen diameter narrowing <50%).

CONCLUSIONS: In a real-world practice of ACS, underutilization of evidence-based medications in patients with NC or NOCAD was observed. Nonetheless, its prognostic significance is still unknown and must be explored in larger patient cohorts.

METHODS: The Acute Coronary Syndrome Israeli Survey (ACSIS) database was utilized to compare the characteristics and therapeutic approach for patients who underwent angiography for ACS and had either NC (n = 84; 2%), NOCAD (n = 79; 2%), or obstructive coronary artery disease (OCAD; n = 3523; 96%).

OBJECTIVES: To explore the characteristics and management strategies in this population in a real-world setting.

RESULTS: Baseline characteristics were comparable, save for a younger age and a higher proportion of females in the NC group (P<.001 for both). Prior to admission, chronic anticoagulant therapy was more frequently used in the NC vs. the OCAD group (4.8% vs. 1.6%, respectively; P=.02). Recommended ACS evidence-based medications, both in-hospital and at discharge, were less frequently prescribed to patients with NC or NOCAD.

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