Sleep-apnea risk and subclinical atherosclerosis in early-middle-aged retired National Football League players.

MedStar author(s):
Citation: Nature & Science of Sleep. 9:31-38, 2017PMID: 28260958Institution: MedStar Health Research Institute | MedStar Union Memorial HospitalDepartment: MedStar Sports Medicine | Sports Medicine Research CenterForm of publication: Journal ArticleMedline article type(s): Journal ArticleSubject headings: PubMed-not-MEDLINE -- Not indexedYear: 2017ISSN:
  • 1179-1608
Name of journal: Nature and science of sleepAbstract: CONCLUSION: Retired NFL players have a greater prevalence of high SA risk but similar prevalence of CAC compared with a well-matched community cohort.MATERIALS AND METHODS: Retired NFL players (n=122) were matched to CARDIA Sleep participants by age +/-2 years (range 37-55 years), body mass index +/-2 kg/m<sup>2</sup>, race, and male sex. Participants underwent electron-beam computed tomography to measure coronary artery calcium (CAC) and completed the Berlin Questionnaire to determine SA risk. The presence of CAC was defined as an Agatston score >0.PURPOSE: Limited data from former National Football League (NFL) players suggest that obstructive sleep apnea (OSA) may be highly prevalent after retirement. It remains unclear whether the high prevalence of OSA in retired players is comparable to nonathletes. This retrospective analysis compared sleep apnea (SA) risk in retired NFL players to a community cohort (CARDIA Sleep study), and examined associations between SA risk and cardiovascular risk factors, including subclinical atherosclerosis.RESULTS: Retired NFL players had a greater prevalence of high SA risk than the matched CARDIA Sleep participants (27% vs 11.5%, P=0.002). Compared to the CARDIA Sleep participants, retired players were less likely to smoke, and had higher blood pressure, lower fasting glucose levels, and higher cholesterol levels. However, there was no difference in the prevalence of detectable CAC (30% vs 30%, P=1). In both players and the community cohort, SA risk was not significantly associated with CAC after controlling for age, race, and body mass index.All authors: Carnethon MR8:56 AM 6/16/2017, Dunn RE, Knutson KL, Lauderdale DS, Lincoln AE, Luyster FS, Pellman EJ, Strollo PJ Jr, Tucker AM, Vogel RAFiscal year: FY2017Digital Object Identifier: Date added to catalog: 2017-06-16
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Journal Article MedStar Authors Catalog Article 28260958 Available 28260958

CONCLUSION: Retired NFL players have a greater prevalence of high SA risk but similar prevalence of CAC compared with a well-matched community cohort.

MATERIALS AND METHODS: Retired NFL players (n=122) were matched to CARDIA Sleep participants by age +/-2 years (range 37-55 years), body mass index +/-2 kg/m<sup>2</sup>, race, and male sex. Participants underwent electron-beam computed tomography to measure coronary artery calcium (CAC) and completed the Berlin Questionnaire to determine SA risk. The presence of CAC was defined as an Agatston score >0.

PURPOSE: Limited data from former National Football League (NFL) players suggest that obstructive sleep apnea (OSA) may be highly prevalent after retirement. It remains unclear whether the high prevalence of OSA in retired players is comparable to nonathletes. This retrospective analysis compared sleep apnea (SA) risk in retired NFL players to a community cohort (CARDIA Sleep study), and examined associations between SA risk and cardiovascular risk factors, including subclinical atherosclerosis.

RESULTS: Retired NFL players had a greater prevalence of high SA risk than the matched CARDIA Sleep participants (27% vs 11.5%, P=0.002). Compared to the CARDIA Sleep participants, retired players were less likely to smoke, and had higher blood pressure, lower fasting glucose levels, and higher cholesterol levels. However, there was no difference in the prevalence of detectable CAC (30% vs 30%, P=1). In both players and the community cohort, SA risk was not significantly associated with CAC after controlling for age, race, and body mass index.

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