Gastric Adenocarcinoma: A Multimodal Approach. [Review]

MedStar author(s):
Citation: Frontiers in Surgery. 4:42, 2017PMID: 28824918Institution: MedStar Health Research Institute | MedStar Washington Hospital CenterDepartment: Surgery/General SurgeryForm of publication: Journal ArticleMedline article type(s): Journal Article | ReviewSubject headings: PubMed-not-MEDLINE -- Not indexedYear: 2017ISSN:
  • 2296-875X
Name of journal: Frontiers in surgeryAbstract: Despite its declining incidence, gastric cancer (GC) remains a leading cause of cancer-related deaths worldwide. A multimodal approach to GC is critical to ensure optimal patient outcomes. Pretherapy fine resolution contrast-enhanced cross-sectional imaging, endoscopic ultrasound and staging laparoscopy play an important role in patients with newly diagnosed ostensibly operable GC to avoid unnecessary non-therapeutic laparotomies. Currently, margin negative gastrectomy and adequate lymphadenectomy performed at high volume hospitals remain the backbone of GC treatment. Importantly, adequate GC surgery should be integrated in the setting of a multimodal treatment approach. Treatment for advanced GC continues to expand with the emergence of additional lines of systemic and targeted therapies.All authors: Al-Refaie WB, Chalhoub WM, Haddad NG, Levy AD, Martin AD, Morales SJ, Phillips AC, Quadri HS, Smaglo BG, Unger KRFiscal year: FY2018Digital Object Identifier: Date added to catalog: 2017-08-29
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Journal Article MedStar Authors Catalog Article 28824918 Available 28824918

Despite its declining incidence, gastric cancer (GC) remains a leading cause of cancer-related deaths worldwide. A multimodal approach to GC is critical to ensure optimal patient outcomes. Pretherapy fine resolution contrast-enhanced cross-sectional imaging, endoscopic ultrasound and staging laparoscopy play an important role in patients with newly diagnosed ostensibly operable GC to avoid unnecessary non-therapeutic laparotomies. Currently, margin negative gastrectomy and adequate lymphadenectomy performed at high volume hospitals remain the backbone of GC treatment. Importantly, adequate GC surgery should be integrated in the setting of a multimodal treatment approach. Treatment for advanced GC continues to expand with the emergence of additional lines of systemic and targeted therapies.

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